Professor Chris McDermott
MBChB, FRCP, PhD
Neuroscience, School of Medicine and Population Health
Professor of Translational Neurology
Honorary Consultant Neurologist
+44 114 222 2295
Full contact details
Neuroscience, School of Medicine and Population Health
91探花 Institute for Translational Neuroscience (SITraN)
385a Glossop Road
91探花
S10 2HQ
- Profile
-
Prof McDermott studied for his medical degree at the University in Leeds graduating in 1994. He then continued is general medical and specialist neurology training in Leeds before taking up a clinical research training fellowship at the University of Newcastle upon Tyne.
He moved to the University of 91探花 with Professor Dame Pamela Shaw in 2000 to undertake his Wellcome Trust Research Training PhD Fellowship and to complete his Specialist Training in Neurology to become a Consultant Neurologist in 2006. Prof McDermott is now the Professor of Translational Neurology at SITraN, an NIHR Research Professor and a Consultant Neurologist at the 91探花 Teaching Hospitals Foundation NHS Trust regularly undertaking specialist MND and neuromuscular clinics in 91探花.
The main drive of Prof McDermott鈥檚 research programme is evaluating the new treatments for motor neuron disease. He is also passionate about developing the evidence base for delivering supportive and symptomatic care for patients living with motor neuron disease now.
- Qualifications
-
2021 鈥 to date
NIHR Research Professor
2018 - 2022
Professor of Translational Neurology
Head of Department2017 鈥 to date
Professor of Translational Neurology
Academic Director for Neuroscience, 91探花 Teaching Hospitals NHS Foundation Trust2006 - 2013
Clinical Senior Lecturer in Neurology2002 - 2006
Specialist Training in Neurology (CCT), 91探花
2000 - 2002
Wellcome Trust Research Training Fellowship (PhD), University of 91探花
1998 - 2000
Clinical Research Fellow, University of Newcastle upon Tyne
1997 - 1998
Specialist Training in Neurology, Leeds
1994 - 1997
General professional training (MRCP), Leeds Teaching Hospitals
1989 - 1994
Medicine (MBChB), University of Leeds
- Research interests
-
Current Projects
- Designing and conducting clinical trials in MND
- Collaborating with pharmaceutical companies in Phase 1-3 studies
- Improving symptomatic management for patients with MND
- Developing and evaluating novel service delivery mechanisms for patients with MND and long term neurological conditions
- Investigating optimal respiratory support for patients with MND
- Establishing an evidence base for nutritional support in MND
- Exploring the role of the microbiome in MND
- Designing and evaluating assistive technologies for patients with neuromuscular weakness
- Genetic and phenotypic characterisation of motor system disorders
- Natural history study of motor system disorders
- Designing and conducting clinical trials in MND
- Collaborating with pharmaceutical companies in Phase 1-3 studies
- Improving symptomatic management for patients with MND
- Epidemiology of motor neuron disease
- Publications
-
Journal articles
- . Journal of Neurology, 272(1).
- . The Cognitive Behaviour Therapist, 17.
- . The Lancet Neurology, 23(11), 1097-1107.
- . Health and Quality of Life Outcomes, 22(1).
- . Neurology, 103(2).
- , 119-169.
- . The Lancet.
- . European Journal of Neurology.
- . The Analyst.
- . Translational Neurodegeneration, 12(1).
- . Clinical Nutrition ESPEN, 57, 839-839.
- . Clinical Nutrition ESPEN.
- . Pilot and Feasibility Studies, 9.
- . Neurology, Publish Ahead of Print.
- . Trials, 24.
- . Journal of the Neurological Sciences, 444, 120483-120483.
- . BMC Neurology, 22(1).
- . Amyotroph Lateral Scler Frontotemporal Degener, 1-9.
- . New England Journal of Medicine, 387(12), 1099-1110.
- . BMJ Open, 12(6).
- . Clinical Neurophysiology.
- . European Journal of Human Genetics.
- . Clinical Nutrition ESPEN.
- . Annals of Neurology, 91(4), 521-531.
- . Clinical Neurophysiology, 138, 231-240.
- . Analyst.
- . Muscle & Nerve.
- . Amyotroph Lateral Scler Frontotemporal Degener, 1-5.
- . Journal of the Neurological Sciences, 429, 119412-119412.
- . Amyotroph Lateral Scler Frontotemporal Degener, 1-10.
- . J Med Internet Res, 23(9), e28766.
- . Amyotroph Lateral Scler Frontotemporal Degener, 1-10.
- . Brain Sciences, 11(8).
- . J Neurol Neurosurg Psychiatry.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Amyotroph Lateral Scler Frontotemporal Degener, 1-10.
- . BMC Medicine, 19(1).
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(1-2), 154-160.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(3-4), 316-319.
- . Journal of the Neurological Sciences, 421, 117285-117285.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(7-8), 592-594.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Clinical Nutrition ESPEN, 40, 519-519.
- . Physiological Measurement, 41(12).
- . New England Journal of Medicine, 383(2), 109-119.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21(3-4), 314-319.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21(5-6), 477-483.
- . Clinical Nutrition ESPEN, 35, 235-235.
- . Clinical Neurophysiology.
- . Journal of Neurology, 267(3), 616-617.
- . Journal of Neurology, 267(1), 257-258.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21(7-8), 642-647.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21(1-2), 154-157.
- . Amyotroph Lateral Scler Frontotemporal Degener, 21(1-2), 150-153.
- . Developmental Medicine & Child Neurology, 62(3), 270-270.
- . Journal of Neurology, Neurosurgery & Psychiatry, 91(1), 7-7.
- . Journal of Neurology, 267(3), 607-615.
- . BMJ Open, 9(12).
- . Clinical Nutrition.
- . BMJ Open, 9(10).
- . BMJ Open, 9.
- . British Journal of Health Psychology.
- . Current Opinion in Neurology, 32(5), 758-763.
- . Practical Neurology, 19(6), 467-475.
- . European Respiratory Journal.
- . Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration.
- . Neurology, 93(1), e59-e76.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20(7-8), 625-629.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20(5-6), 317-327.
- . Acta Neurologica Scandinavica, 140(2), 131-139.
- . Neurology, 92(15_supplement).
- . Neurology, 92(15_supplement).
- . Neurology, 92(15_supplement).
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20(7-8), 619-624.
- . Neurology.
- . Cell Reports, 26(9), 2298-2306.e5.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20(1-2), 74-81.
- . The Lancet Neurology, 18(3), 259-268.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20(1-2), 126-131.
- . Neurology Genetics, 4(6), e279-e279.
- . Disability and Rehabilitation: Assistive Technology.
- . Brain, 141(10), 2866-2877.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(5-6), 472-476.
- . Clinical Biomechanics, 57, 114-120.
- . The Lancet Neurology, 17(5), 423-433.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(7-8), 630-634.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(7-8), 623-629.
- . Journal of Neuromuscular Diseases, 5(1), 107-107.
- . Journal of Neurology, Neurosurgery, and Psychiatry, 89, 248-255.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(5-6), 351-361.
- . Ergonomics, 61(2), 329-338.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(1-2), 157-160.
- . Acta Neurologica Scandinavica, 138(1), 47-54.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(3-4), 317-319.
- . Journal of Neurology, Neurosurgery & Psychiatry, 88(Suppl 1), A63.4-A64.
- . Frontiers in Molecular Neuroscience, 10, 370-370.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Neurology.
- . Practical Neurology, 17(5), 339-340.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18(7-8), 627-631.
- . Journal of the Peripheral Nervous System, 22(2), 68-76.
- . BMJ Supportive & Palliative Care, 7(2), 189-196.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18(5-6), 313-323.
- . BMC Health Services Research, 17.
- . Practical Neurology, 17(2), 96-103.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18(5-6), 466-469.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 18(5-6), 378-387.
- . BMJ Supportive and Palliative Care.
- . PLoS One.
- . Amyotrophic Lateral Sclerosis && Frontotemporal Degeneration, 18(1-2), 1-9.
- . Cochrane Database of Systematic Reviews, 2016(12).
- . Practical Neurology, 16, 352-361.
- . Gait & Posture, 49, S22-S22.
- . Medicine, 44(9), 552-556.
- . Muscle & Nerve, 54(3), 378-385.
- . Nature Reviews Neurology, 12, 526-538.
- . Health Technol Assess, 20(45), 1-186.
- . European Journal of Neurology, 23(6), 1071-1078.
- . Neuropathology, 36(2), 125-134.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17(5-6), 325-336.
- . Amyotrophic Lateral Sclerosis && Frontotemporal Degeneration, 17(5-6), 313-324.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17(5-6), 377-384.
- . Amyotrophic Lateral Sclerosis, 17(5-6), 436-442.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17(3-4), 305-306.
- . Practical Neurology, 16(3), 227-230.
- . Clinical Biomechanics, 32, 201-206.
- . BMJ Support Palliat Care, 6(1), 52-59.
- . The Lancet Neurology, 14(12), 1153-1153.
- . Environmental Earth Sciences, 74(12), 7837-7854.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(7-8), 448-455.
- . The Lancet Neurology, 14(9), 883-892.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(7-8), 478-484.
- . The Lancet Neurology, 14(7), 702-709.
- . Neuropathol Appl Neurobiol, 41(2), 201-226.
- . The Lancet Neurology, 14(7), 690-690.
- . Journal of Medical Engineering & Technology, 39(7), 404-410.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16(1-2), 108-113.
- . Neuropathol Appl Neurobiol, 40(6), 670-685.
- . Current Opinion in Neurology, 27(5), 524-531.
- . BMJ Supportive & Palliative Care, 4(Suppl 1), A39.1-A39.
- . BMJ Supportive & Palliative Care, 4(Suppl 1), A25.1-A25.
- . BMJ Support Palliat Care, 4(1), 57-63.
- . Acta Neuropathol, 127(3), 407-418.
- . Dis Model Mech, 7(1), 73-81.
- . J Palliat Med, 16(12), 1602-1609.
- . Palliat Med, 27(9), 878.
- . Neuro-Ophthalmology, 37(4), 146-156.
- . Neurology, 81(9), 808-811.
- . Amyotroph Lateral Scler Frontotemporal Degener, 14(5-6), 414-423.
- . Amyotroph Lateral Scler Frontotemporal Degener, 14(7-8), 521-527.
- . The Lancet Neurology, 12(4), 339-345.
- . Palliat Med, 27(6), 516-523.
- . Neuropathol Appl Neurobiol, 39(5), 562-571.
- . J Neurol Neurosurg Psychiatry, 84(1), 79-87.
- . Amyotroph Lateral Scler Frontotemporal Degener, 14(2), 96-104.
- . Amyotroph Lateral Scler Frontotemporal Degener, 14(2), 105-110.
- . Amyotroph Lateral Scler Frontotemporal Degener, 14(1), 13-19.
- . Amyotroph Lateral Scler, 13(6), 528-532.
- . Pract Neurol, 12(3), 166-176.
- . BMJ Supportive & Palliative Care, 2(Suppl 1), A102.3-A103.
- . Brain, 135(Pt 3), 751-764.
- . Medicine (United Kingdom), 40(10), 540-545.
- . BMC Neurol, 12, 74.
- . Journal of Neurology, Neurosurgery & Psychiatry, 83(4), 368-369.
- . Journal of Neurology, Neurosurgery and Psychiatry, 83(4), 371-376.
- . J Neurol Neurosurg Psychiatry, 83(4), 371-376.
- Multiple sclerosis and amyotrophic lateral sclerosis - what is the link? A case series of six patients. MULTIPLE SCLEROSIS JOURNAL, 17, S472-S472.
- . BMC Neurology, 11.
- . BRIT MED J, 341.
- Non-invasive ventilation in motor neurone disease: an update of current UK practice. IRISH J MED SCI, 179, S497-S498.
- . INT J BEHAV NUTR PHY, 7.
- . Amyotroph Lateral Scler, 11(6), 531-536.
- . J Neurol Neurosurg Psychiatry, 81(6), 646-649.
- . Neurogenetics, 11(2), 217-225.
- . Arch Neurol, 67(4), 455-461.
- . InnovAiT: Education and inspiration for general practice, 2(9), 531-537.
- . Amyotroph Lateral Scler, 10(4), 191-204.
- . Neurology, 72(17), 1534-1534.
- . Neurogenetics, 10(2), 105-110.
- . The Lancet Neurology, 8(2), 158-164.
- . J Neurochem, 110(1), 34-44.
- . Neurology, 70(19), 1717-1718.
- . Clinical Neurophysiology, 119, S111-S111.
- . BMJ, 336(7645), 658-662.
- . Medicine, 36(12), 640-645.
- . HUM MUTAT, 28(7), 739-740.
- . Handbook of Clinical Neurology, 82, 327-352.
- . Hum Mol Genet, 15(18), 2763-2771.
- . Marine Ecology Progress Series, 320, 259-266.
- . Neurology, 67(1), 45-51.
- , 435-462.
- . Ann Neurol, 54(6), 748-759.
- . J Neuropathol Exp Neurol, 62(11), 1166-1177.
- . Amyotroph Lateral Scler Other Motor Neuron Disord, 4(2), 96-99.
- . Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders, 4(2), 96-99.
- . Neuroreport, 14(3), 485-488.
- Investigation of mitochondrial function in hereditary spastic paraparesis. J NEUROL NEUROSUR PS, 73(2), 233-233.
- . Int Rev Neurobiol, 53, 191-204.
- . Neuroreport, 12(11), 2319-2322.
- . Neurology, 56(4), 467-471.
- Genotype-phenotype correlation in hereditary spastic paraparesis. J NEUROL NEUROSUR PS, 70(2), 270-270.
- . J Med Genet, 37(10), 759-765.
- . J Neurol Neurosurg Psychiatry, 69(2), 150-160.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-14.
- . Brain.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-12.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . JMIR Research Protocols, 13, e57685-e57685.
- . Nutrition Reviews.
- . European Journal of Neurology.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-11.
- . PharmacoEconomics.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . European Journal of Neurology.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-11.
- . Journal of Medical Genetics.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-10.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-6.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-3.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Trials, 24(1), 792.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-10.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-10.
- . Nature Reviews Neurology.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . Health Expectations.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . European Journal of Neurology.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . ERJ Open Research, 00388-2022.
- . Journal of Raman Spectroscopy.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . Frontiers in Neurology, 13.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-7.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-8.
- . Journal of Medical Engineering & Technology, 1-9.
- . Journal of Neurology.
- . Brain Communications.
- . Journal of Medical Engineering & Technology, 1-12.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-8.
- . Brain Communications.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Brain.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Physiological Measurement.
- . Neurology, 10.1212/WNL.0000000000012545-10.1212/WNL.000000000.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Journal of Human Nutrition and Dietetics.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-5.
- . Nature Reviews Neurology.
- . Journal of Neurology, Neurosurgery & Psychiatry.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-9.
- . Cochrane Database of Systematic Reviews.
- . Journal of Neurology.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-8.
- Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis. Brain.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-4.
- . Journal of Raman Spectroscopy.
- Patient, carer and healthcare professional perspectives on increasing calorie intake in Amyotrophic Lateral Sclerosis. Chronic Illness.
Chapters
- , Public Policy in ALS/MND Care (pp. 279-300). Springer Singapore
- , Nutrition in Neurologic Disorders (pp. 91-104). Springer International Publishing
Conference proceedings papers
- . Neurology, Vol. 102(17_supplement_1)
- . Free Papers 18鈥20: Non-Malignant Disease
- Discovering disease specific metabolites in Amyotrophic Lateral Sclerosis (ALS): new direction to personalised medicine?. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 30 (pp 51-52)
- . Clinical Nutrition ESPEN, Vol. 48 (pp 510-510). Brighton, UK, 30 November 2021 - 1 December 2021.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 22(suppl 2) (pp 171-171). Virtual, 7 December 2021 - 10 December 2021.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 22(sup2) (pp 232-233). Virtual conference, 7 December 2021 - 10 December 2021.
- Understanding Clinical Heterogeneity in Amyotrophic Lateral Sclerosis (ALS) - A Systematic Literature Review. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 28 (pp 398-399)
- . Journal of Neurology Neurosurgery & Psychiatry, Vol. 90(12) (pp e10)
- . Journal of Neurology Neurosurgery & Psychiatry, Vol. 90(12) (pp e55)
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 20(suppl 1) (pp 310-310). Perth, Australia, 4 December 2019 - 6 December 2019.
- Defining benign brachial monomelic amyotrophy: factors at presentation that differentiate from motor neurone disease. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 26 (pp 307-307)
- Monitoring and promoting effectiveness and adherence to non-invasive ventilation in motor neurone disease using Encore Anywhere telemonitoring: a pilot and feasibility, randomised controlled trial. NEUROLOGY, Vol. 92(15)
- Predicting benign brachial monomelic amyotrophy: factors at presentation that differentiate from amyotropic lateral sclerosis. NEUROLOGY, Vol. 92(15)
- Investigating Directionality of Neurodegeneration in vivo in ALS using Multimodal MRI. NEUROLOGY, Vol. 92(15)
- MUTATIONS IN THE GLYCOSYLTRANSFERASE DOMAIN OF GLT8D1 CAUSE ALS. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 90(12) (pp E20-E21)
- . Annals of Physical and Rehabilitation Medicine, Vol. 61 (pp e521-e521)
- Imaging denervation in amyotrophic lateral sclerosis for future clinical trials: 12-month follow-up from a longitudinal cohort study. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 25 (pp 302-302)
- . Journal of the Neurological Sciences, Vol. 381 (pp 304-305)
- . Journal of the Neurological Sciences, Vol. 381 (pp 707-707)
- . Journal of the Neurological Sciences, Vol. 381 (pp 102-102)
- The development of an evidence based guideline on the assessment and management of motor neurone disease/amyotrophic lateral sclerosis. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 23 (pp 646-646)
- . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 86(11) (pp e4.54-e4)
- Elevated creatine kinase is associated with a better prognosis in patients with amyotrophic lateral sclerosis. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 22 (pp 741-741)
- Effects of cough augmentation on pulmonary morbidity, survival, and quality of life in patients with amyotrophic lateral sclerosis in respiratory failure: a randomised trial. EUROPEAN JOURNAL OF NEUROLOGY, Vol. 22 (pp 244-244)
- . Journal of Neurology, Neurosurgery & Psychiatry, Vol. 85(10) (pp e4.93-e4)
- . J Neurol Neurosurg Psychiatry, Vol. 84(11) (pp e2). England
- Neurodegeneration caused by intronic expansions of C9ORF72 is a clinically heterogeneous but pathologically distinct disease. LANCET, Vol. 381 (pp 32-32)
- . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 83
- . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 83(3)
- . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 83(3)
- The Use of Non-Invasive Ventilation for Patients with Motor Neurone Disease: Patient and Carer Perceptions of Obstacles and Outcomes. ANNALS OF NEUROLOGY, Vol. 72 (pp S73-S74)
- The Environmental Legacy of Historic Mining Activities in the Almond River Catchment, Scotland. MINE WATER - MANAGING THE CHALLENGES: PROCEEDINGS OF THE INTERNATIONAL MINE WATER ASSOCIATION CONGRESS 2011 (pp 581-586)
- . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 81(11) (pp E50-E50)
- . Anaesthesia, Vol. 65(1) (pp 112-113)
- . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 80(11)
- CLINICAL AND NEUROPHYSIOLOGICAL SIMILARITIES BETWEEN TOXIC AND ACQUIRED INFLAMMATORY DEMYELINATING NEUROPATHIES: A REPORT OF TWO CASES. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 80(1) (pp 123-123)
- CLINICAL AND NEUROPHYSIOLOGICAL FINDINGS IN HEREDITARY NEUROPATHY WITH LIABILITY TO PRESSURE PALSIES. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 80(1) (pp 101-102)
- Further insights into HSP and spastin: Severe complicated phenotypes and evidence of lower motor neurone dysfunction. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 77(1) (pp 137-137)
- Hereditary spastic paraparesis associated with mutation in spastin (SPG4): A disorder of axonal transport?. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 74(10) (pp 1453-1453)
- The results of screening all 17 exons of the spastin gene (SPG4) for autosomally dominantly transmitted Hereditary Spastic Paraplegia. JOURNAL OF MEDICAL GENETICS, Vol. 40 (pp S81-S81)
- Hereditary spastic paraparesis with amyotrophy and OXPHOS muscle defect associated with a deletion in the paraplegin (SPG7) gene with apparent autosomal dominant transmission. NEUROLOGY, Vol. 54(7) (pp A425-A425)
Reports
- NIV withdrawal guidance 鈥 published by Association of Palliative Medicine of GB and Northern Ireland.
Other
Preprints
- Research group
-
- Esther Hobson
- Alys Griffiths
- Theocharis Stavroulakis
- Liam Knox
- Mbombe Kazoka
- Stacy Young
- Lee Tuddenham
- Sarah Boddy
- Emily Mayberry
- Sean White
- Jade Howard
- Harry McDonnogh
- Madalina Roman
- Mary Sikonga
- Leslie Ing
- Lucy Musson
- Charlotte Massey
- Jon Street
- Sarah Roscoe
- Grants
-
Principal Funding Sources
- Motor Neurone Disease Association, UK
- National Institute of Health Research (NIHR)
- LifeArc
- My Name鈥5 Doddie Foundation
- European Union
- Professional activities and memberships
-
- Co-Director UK MND Research Institute (2022 onwards)
- Neuroscience Theme Lead at NIHR 91探花 Biomedical Research Centre (2022 onwards)
- NIHR Research Professor (2021-onwards)
- Head of Department, Neuroscience, University of 91探花 (2018-2022 onwards)
- Chair of Association of British Neurologists MND Special Interest Group (2017 onwards)
- Member of Association of British Neurologists Neuromuscular Advisory Group (2018-2022 onwards)
- Deputy Director of NIHR BRC 91探花 (2017-2022 onwards)
- External Examiner Neuroscience MSc, Kings College London (2016 -2020)
- Expert Advisor for NICE (2016 onwards)
- Charitable Trustee for Neurocare (2016 onwards)
- Group Leader for the International ALS Clinical Trials Guidelines (2015-2017).
- Chair of the NIHR DeNDRoN MND Clinical Studies Group (2015 onwards)
- Chair of the MND Association Clinical Advisory Board (2015 onwards)
- Member MND NICE Clinical Guidelines Development Group (2013 鈥 2016) and NICE Quality Assurance panel (2015 - 2016).
- Founding Course Leader 鈥 Clinical Neurology MSc, University of 91探花 (2011-2015)
- Clinical Lead for Neurology, 91探花 Teaching Hospitals (2012-2014)
- Member of NIHR RfPB (2010-2014) and MNDA healthcare research grant panels (2014 onwards).
- Representation of the Yorkshire and Humber region nationally on the Joint Royal College of Physician鈥檚 Specialty Advisory Committee (2008 - 2013).
- Training Programme Director for Neurology Yorkshire and Humber (2008-2012)
- Invited lectures
2017
- NICE Guidelines 1 year on Conference, London UK - Managing Symptoms in MND at the MND
- Association British Neurologists Meeting, Liverpool - Right to try
- MND Care Centre Meeting, Kettering - MyTube
- NIHR Annual CRF conference, Glasgow - User Centred Design
- Newcastle Neurosciences Meeting, Newcastle upon Tyne - MND A Journey through time and space
- MND Scotland meeting, Stirling - MND Clinical Research update
- Oxford Neurosciences Meeting, Oxford - MND Surviving the experts
2016
- Manchester Regional Neurosciences Centre 鈥 The evidence base for supportive Care in ALS.
- Newcastle upon Tyne, MND study day 鈥 Delivering evidence based care for individuals with ALS.
- 91探花 MND Study day 鈥 Recent developments in ALS care.
- St Christopher鈥檚 Hospice, London 鈥 Nutritional Care in ALS.
- Primary Care 2016, NEC, Birmingham 鈥 NICE guidelines for primary care.
2015
- British Thoracic Society, London 鈥 Diaphragmatic Pacing in ALS
- Difficult Lung Disease symposium, 91探花 鈥 Neuromuscular disease for the respiratory physician.
- MNDA Care Centre meeting, Stafford - myNIV
- Association of palliative medicine neurological palliative care specialist interest forum, Manchester 鈥 What is new in MND.
- 1st UK PLS conference, Oxford 鈥 HSP and PLS
- WFN ALS meeting, Orlando 鈥 DiPALS results
2014
- MNDA Care Centre meeting, Stafford 鈥 Head Up
- Royal Society Medicine, London 鈥 The evidence base for symptomatic care in ALS
- MND Centre, Oxford 鈥 Update on symptomatic care.
- The Walton Centre, Liverpool - Update on symptomatic care.
- St Christopher鈥檚 Hospice, London 鈥 Head Up.
- Royal College of Physicians Regional Update, 91探花 鈥 Neurology for the physician.
2013
- Plenary speaker: ENCALS, 91探花 - While we wait.
- MND Care Centre Directors meeting, Birmingham 鈥 Head Up and Secretion management
- St Christopher鈥檚 Hospice, London 鈥 Diaphragmatic Pacing
- The Walton Centre Regional Neurosciences Centre, Liverpool 鈥 Respiratory management of MND
2012
- Edinburgh Regional Neurosciences Centre - Respiratory management of MND
- Home Mechanical Ventilation Meeting, St Thomas Hospital, London 鈥 Role of Diaphragmatic Pacing
- Palliative Care Symposium, Leeds 鈥 Living with MND
- MNDA AGM 鈥 Developing the evidence base for clinical care in MND
2011
- Association of British Neurologists meeting 鈥 Clinical advances in MND
- European federation of neurological sciences, Lisbon 鈥 MND and its mimics
2010
- European Federation of Neurological Sciences, Rhodes - Lump or Split?
- MNDA Birmingham 鈥 Diaphragmatic Pacing in MND
- Nutrition Course, Leeds 鈥 Nutrition in MND
2009
- Leeds MNDA centre opening 鈥 Hereditary spastic paraparesis