Professor Nils P Krone
MD, FRCPCH
Clinical Medicine, School of Medicine and Population Health
Professor of Paediatric Endocrinology
Honorary Consultant Paediatric Endocrinologist
+44 114 271 7508
Full contact details
Clinical Medicine, School of Medicine and Population Health
Room 16, The Damer Street Building
91探花 Children's Hospital
Western Bank
91探花
S10 2TH
- Profile
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For enquiries please contact - ClinMed-Operational@sheffield.ac.uk
I graduated from the Ludwig-Maximilian鈥檚 University, Munich, Germany, where I was also awarded my MD for studies into the genotype-phenotype correlation in congenital adrenal hyperplasia. I have trained in General Paediatrics and Paediatric Endocrinology at the University Children鈥檚 Hospital, Munich and University of Kiel Children鈥檚 Hospital, Germany (1999-2006). I have been working at the University of Birmingham as Wellcome Trust Clinician Scientist and Senior Clinical Lecturer (2006-2015).
I was appointed at the University of 91探花 in 2015 and work as Honorary Consultant Paediatric Endocrinologist at 91探花 Children鈥檚 Hospital, where I lead the adrenal and disorders/ differences of sex development (DSD) clinical service.
Current PhD Opportunities:
- Research interests
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My main clinical and basic research interests are inborn errors of steroid hormone biosynthesis and steroid hormone metabolism in health and disease. This is closely interlinked with my main clinical interests into inborn errors of steroidogenesis, congenital adrenal hyperplasia (CAH), disorders/ differences of sex development (DSD), and PCOS.
Ongoing work of my group explores the systemic consequences of disrupted steroid hormone synthesis and action on whole organism employing zebrafish as a model organism in translational steroid hormone research. This research is based at the Bateson Centre.
The main focus of my clinical research program is on CAH. I led on several projects to establish the evidence basis on the current health status in children and young people with congenital adrenal hyperplasia in the UK as well as standardisation of healthcare provision.
In addition, I work on a program to improve health care deliver for children and young people with DSD .
Current projects
- Understanding the systemic consequences to disrupted steroidogenesis.
- Long-term pathophysiology of glucocorticoid deficiency
- Health status of children and young persons with congenital adrenal hyperplasia (CAH-UK).
- Improving biomarkers for therapy monitoring in CAH.
- Current practice of CAH healthcare delivery in the UK.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . Molecular and Cellular Endocrinology, 535, 111372-111372.
- . The Lancet, 397(10274), 613-629.
- . Journal of Endocrinology, 247(2), 197-212.
- . Journal of Endocrinology, 244(2), 309-321.
- . The Journal of Clinical Endocrinology & Metabolism, 104(12), 6417-6429.
- . Proceedings of the National Academy of Sciences, 116(44), 22269-22274.
- . Endocrinology.
- . European Journal of Endocrinology, 179(4), R197-R206.
- . EBioMedicine, 36, 376-389.
- . Journal of Neuroendocrinology, 30(4).
- . Endocrinology, 158(12), 4165-4173.
All publications
Journal articles
- . Journal of the Endocrine Society, 8(Supplement_1).
- . Clin Endocrinol (Oxf).
- . Pediatric Allergy, Immunology, and Pulmonology, 36(3), 94-103.
- . Journal of the Endocrine Society, 7(5).
- . Journal of the Endocrine Society, 6(Supplement_1), A621-A621.
- . Journal of the Endocrine Society, 6(Supplement_1), A592-A592.
- . European Journal of Endocrinology, 187(4), 543-553.
- . Hormone and Metabolic Research, 54(08), 532-539.
- . Hormone Research in Paediatrics.
- . European Journal of Endocrinology.
- . European Journal of Endocrinology, 185(5), 729-741.
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- . European Journal of Endocrinology, 184(6), 791-801.
- . Molecular and Cellular Endocrinology, 535, 111372-111372.
- . Clin Endocrinol (Oxf).
- . Journal of the Endocrine Society.
- . Journal of the Endocrine Society, 5(Suppl 1), a720-a720.
- . Journal of the Endocrine Society, 5(Suppl 1), a717-a717.
- . The Lancet, 397(10274), 613-629.
- . European Journal of Endocrinology.
- . Journal of Endocrinology, 247(2), 197-212.
- .
- . eLife, 9.
- . European Journal of Endocrinology, 182(6), P1-P15.
- . Journal of Endocrinology, 244(2), 309-321.
- . The Journal of Clinical Endocrinology & Metabolism, 105(1), 314-326.
- . The Journal of Clinical Endocrinology & Metabolism, 104(12), 6417-6429.
- . Proceedings of the National Academy of Sciences, 116(44), 22269-22274.
- . Proceedings of the National Academy of Sciences, 116(44), 22294-22299.
- . Endocrinology.
- . Archives of Disease in Childhood.
- . Endocrine Connections.
- . Molecular Psychiatry, 24(1), 2-9.
- . European Journal of Endocrinology.
- . Hormone Research in Paediatrics, 90(4), 236-246.
- . European Journal of Endocrinology, 179(4), R197-R206.
- . EBioMedicine, 36, 376-389.
- . Journal of Neuroendocrinology, 30(4).
- . Clinical Endocrinology, 88(5), 744-751.
- . The Journal of Clinical Endocrinology & Metabolism, 103(4), 1330-1341.
- . Endocrinology, 158(12), 4165-4173.
- . Journal of Clinical Endocrinology and Metabolism, 102(3), 1044-1050.
- . European Journal of Endocrinology.
- . Archives of Disease in Childhood.
- . PLoS Genetics, 12(12).
- . The Journal of Clinical Endocrinology & Metabolism, jc.2016-2855-jc.2016-2855.
- . Clinical Endocrinology, 84(5), 771-788.
- . Eye, 30(7), 987-981.
- . Endocrinology, 157(3), 1122-1134.
- . Clinical Endocrinology, 83(5), 629-635.
- . Endocrinology, 156(10), 3504-3510.
- . Endocrinology, 156(8), 2863-2871.
- . Best Practice & Research Clinical Endocrinology & Metabolism, 29(3), 449-468.
- . Hormone Research in Paediatrics, 83(6), 414-421.
- . Clinical Endocrinology, 82(4), 478-480.
- . Sexual Development, 9(2), 91-97.
- . Srpski arhiv za celokupno lekarstvo, 142(11-12), 728-731.
- . PEDIATRICS, 134(3), e710-e715.
- . The Journal of Clinical Endocrinology & Metabolism, 99(8), E1547-E1555.
- . The Journal of Clinical Endocrinology & Metabolism, 99(5), E821-E831.
- . Clinical Endocrinology, 80(4), 469-470.
- . The Journal of Clinical Endocrinology & Metabolism, 99(2), E348-E355.
- . Sexual Development, 8(4), 151-155.
- . The Journal of Clinical Endocrinology & Metabolism, 98(11), E1820-E1826.
- . The Journal of Clinical Endocrinology & Metabolism, 98(10), E1620-E1625.
- . Endocrinology, 154(8), 2702-2711.
- . European Journal of Endocrinology, 168(6), 887-893.
- . The Journal of Clinical Endocrinology & Metabolism, 98(3), E528-E536.
- . European Journal of Endocrinology, 168(2), K19-K26.
- . Clinical Endocrinology, 78(2), 197-203.
- . The Journal of Clinical Endocrinology & Metabolism, 98(2), E346-E354.
- . European Journal of Endocrinology, 167(6), 881-885.
- . The Journal of Clinical Endocrinology & Metabolism, 97(3), E465-E475.
- . The Journal of Clinical Endocrinology & Metabolism, 97(2), E257-E267.
- . The Journal of Clinical Endocrinology & Metabolism, 96(12), 3775-3784.
- . Practical Diabetes, 28(9), 384-387.
- . The Journal of Clinical Endocrinology & Metabolism, 96(11), E1798-E1806.
- . European Journal of Endocrinology, 165(2), 189-207.
- . Clinical Endocrinology, 75(1), 12-26.
- . The Journal of Clinical Endocrinology & Metabolism, 96(3), E453-E462.
- . Endocrinology, 152(2), 741-742.
- . Endocrine Reviews, 32(1), 155-155.
- . Hormone Research in Paediatrics, 76(2), 73-85.
- . The Journal of Clinical Endocrinology & Metabolism, 95(11), 5110-5121.
- . The Journal of Steroid Biochemistry and Molecular Biology, 121(3-5), 496-504.
- . The Journal of Clinical Endocrinology & Metabolism, 95(7), 3418-3427.
- . The Journal of Clinical Endocrinology & Metabolism, 95(5), 2443-2450.
- . Endocrinology, 151(2), 839-839.
- . The Journal of Clinical Endocrinology & Metabolism, 95(2), 779-788.
- . The British Journal of Diabetes & Vascular Disease, 9(6), 259-267.
- . The Journal of Clinical Endocrinology & Metabolism, 94(10), 3865-3871.
- . The Journal of Clinical Endocrinology & Metabolism, 94(8), 3058-3064.
- . Nature Reviews Endocrinology, 5(7), 362-363.
- . Paediatrics and Child Health, 19(7), 309-315.
- . New England Journal of Medicine, 360(22), 2310-2318.
- . Best Practice & Research Clinical Endocrinology & Metabolism, 23(2), 181-192.
- . Human Mutation, 30(2), E443-E450.
- . Clinical Endocrinology, 70(2), 252-258.
- . Hormone Research, 72(5), 281-286.
- . Klinische P盲diatrie, 220(05), 287-290.
- . The Journal of Clinical Endocrinology & Metabolism, 93(7), 2891-2895.
- . Nature Clinical Practice Endocrinology & Metabolism, 3(11), 778-783.
- . Best Practice & Research Clinical Endocrinology & Metabolism, 21(3), 393-401.
- . Molecular Endocrinology, 21(8), 1958-1968.
- . Clinical Endocrinology, 66(2).
- . Hormone Research in Paediatrics, 68(5), 158-164.
- . The Journal of Clinical Endocrinology & Metabolism, 91(12), 4976-4980.
- . The Journal of Clinical Endocrinology & Metabolism, 91(11), 4552-4561.
- . The Journal of Clinical Endocrinology & Metabolism, 91(7), 2682-2688.
- Structure-function relationships in congenital adrenal hyperplasia due to 11-hydroxylase deficiency - insights from two novel mutations (M92X, R453Q) in the CYP11B1 gene. HORMONE RESEARCH, 65, 17-17.
- Naturally occurring mineralocorticoid receptor mutations causing autosomal dominant pseudohypoaldosteronism type 1 (PHA1) - different pathogenetic molecular mechanisms resulting in diverse clinical phenotype. HORMONE RESEARCH, 65, 17-17.
- Functional characterization of a novel missense mutation (P341L) in the HSD3B2 gene causing classic 3beta-hydroxysteroid dehydrogenase deficiency (3 beta-HSD) congenital adrenal hyperplasia (CAH). HORMONE RESEARCH, 65, 116-116.
- . Journal of Molecular Medicine, 83(7), 561-568.
- . European Journal of Pediatrics, 164(6), 397-399.
- . Endocrinology, 146(6), 2563-2574.
- . The Journal of Clinical Endocrinology & Metabolism, 90(6), 3724-3730.
- . Human Mutation, 25(5), 502-502.
- . Human Mutation, 25(5), 443-452.
- . European Journal of Endocrinology, 152(4), 515-519.
- . The Journal of Clinical Endocrinology & Metabolism, 90(1), 445-454.
- . The Journal of Clinical Endocrinology & Metabolism, 89(5), 2150-2152.
- . Hormone Research in Paediatrics, 62(3), 113-118.
- . Hormone Research in Paediatrics, 62(4), 177-181.
- . The Journal of Clinical Endocrinology & Metabolism, 88(4), 1683-1686.
- . Journal of Chromatography B, 785(2), 293-301.
- . Clinical Chemistry, 48(6), 818-825.
- . Hormone Research in Paediatrics, 58(4), 196-205.
- . Clinical Endocrinology, 55(4), 523-529.
- . Journal of Molecular Medicine, 79(10), 581-586.
- . Journal of Clinical Endocrinology and Metabolism, 85(3), 1059-1065.
- A novel frameshift mutation (141delT) in exon 1 of the 21-hydroxylase gene(CYP21) in a patient with the salt wasting form of congenital adrenal hyperplasia. Human Mutation, 14(1), 90-91.
- . Clinical Chemistry, 44(10), 2075-2082.
- The Constitutional Court of the Russian Federation - A judicial institution caught between constitutional duty and political reality. OSTEUROPA, 48(3), 253-267.
- . Endocrine Abstracts.
- . Endocrine Abstracts.
- . Endocrine Abstracts.
- . Journal of the Endocrine Society.
- . Clinical Endocrinology.
- . Hormone Research in Paediatrics.
- . Endocrine Abstracts.
- . Endocrine Abstracts.
- . Endocrine Abstracts.
- . Endocrine Abstracts.
- . Clinical Endocrinology.
- . Hormone Research in Paediatrics, 1-11.
- . Disease Models & Mechanisms.
- . The Journal of Clinical Endocrinology & Metabolism.
- . Archives of Disease in Childhood.
- . Endocrine Abstracts.
- . Clinical Endocrinology.
- . Endocrine Abstracts.
- . Sexual Development, 1-7.
- . Nature Reviews Endocrinology.
- . The Journal of Clinical Endocrinology & Metabolism.
- . Endocrine Abstracts.
- . Endocrine Abstracts.
- . Experimental and Clinical Endocrinology & Diabetes, 114(05), 227-234.
- . Experimental and Clinical Endocrinology & Diabetes, 114(03), 105-110.
- . Experimental and Clinical Endocrinology & Diabetes, 114(03), 111-117.
- . Experimental and Clinical Endocrinology & Diabetes, 114(S 1).
- . Experimental and Clinical Endocrinology & Diabetes, 112(07), 343-355.
- . PLOS Genetics, 16(5).
Chapters
- , Endocrinology (pp. 115-184). Springer International Publishing
- , Endocrinology (pp. 1-70). Springer International Publishing
- , Oxford Textbook of Endocrinology and Diabetes 3e (pp. 931-941). Oxford University Press
- , Oxford Textbook of Medicine (pp. 2360-2373). Oxford University Press
- , P盲diatrische Endokrinologie und Diabetologie (pp. 3-9). Springer Berlin Heidelberg
- , P盲diatrische Endokrinologie und Diabetologie (pp. 1-7). Springer Berlin Heidelberg
- , Understanding Differences and Disorders of Sex Development (DSD) (pp. 41-52). S. KARGER AG
- , Oxford Textbook of Endocrinology and Diabetes (pp. 865-878). Oxford University Press
- The adrenal cortex In Kronenberg HM, Larsen PR, Melmed S, Polonsky KS & Williams RH (Ed.), Williams Textbook of Endocrinology (pp. 479-544). Philadelphia: Elsevier Health Sciences.
- , Williams Textbook of Endocrinology (pp. 479-544). Elsevier
- John Wiley & Sons, Ltd
- John Wiley & Sons, Ltd
Conference proceedings papers
- Trends in glucocorticoid prescribing practice in CAH over the last 6 years (2017-2023). SEXUAL DEVELOPMENT, Vol. 17 (pp 42-45)
- Fifteen years of exome sequencing involving >800 cases of DSD. What have we learned?. SEXUAL DEVELOPMENT, Vol. 17 (pp 73-75)
- Development of the I-HH registry to develop best practice management for hypogonadotropic hypogonadism. SEXUAL DEVELOPMENT, Vol. 17 (pp 95-96)
- Evidence Driven Care in CAH. SEXUAL DEVELOPMENT, Vol. 17 (pp 12-12)
- Acute Adrenal Insufficiency Related Adverse Events In Children With Congenital Adrenal Hyperplasia (CAH): Changes During The Period 2019-2022 In I-CAH. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96 (pp 136-137)
- Management of congenital adrenal hyperplasia in the first 90 days of life: a multi-centre I-CAH analysis of contemporary practice. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96 (pp 29-30)
- National service evaluation project analysing the quality of care for children and young people with congenital adrenal hyperplasia in the United Kingdom: Data from patients and clinicians. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96 (pp 418-419)
- Metabolic effects of cortisol insufficiency are sex-depended in a zebrafish model of 21-hydroxylase deficiency. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96 (pp 135-135)
- The pathophysiologic response of central nervous system due to differently impaired steroidogenesis. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96 (pp 27-28)
- Use of Aromatase inhibitors to improve height outcomes in children with Congenital Adrenal Hyperplasia due to 21 hydroxylase deficiency. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96 (pp 142-143)
- Towards understanding the metabolic phenotype of glucocorticoid deficiency in 21-hydroxylase deficiency. HORMONE RESEARCH IN PAEDIATRICS, Vol. 95(SUPPL 2) (pp 79-79)
- Blood pressure (BP) status in Congenital Adrenal Hyperplasia (CAH) - longitudinal analysis of real world data from the I-CAH registry. HORMONE RESEARCH IN PAEDIATRICS, Vol. 95(SUPPL 2) (pp 112-113)
- Current Management Of Acute Adrenal Insufficiency Related Adverse Events In Children- Results Of An International Survey Of Specialist Centres. HORMONE RESEARCH IN PAEDIATRICS, Vol. 94(SUPPL 1) (pp 125-125)
- Genetic analysis of paediatric primary adrenal insufficiency of unknown aetiology over 25 years. HORMONE RESEARCH IN PAEDIATRICS, Vol. 94(SUPPL 1) (pp 187-188)
- Variation of glucocorticoid dose and biomarkers in children with congenital adrenal hyperplasia longitudinal analysis of real world data from the I-CAH registry. HORMONE RESEARCH IN PAEDIATRICS, Vol. 94(SUPPL 1) (pp 26-26)
- International practice of therapy monitoring in congenital adrenal hyperplasia - Real World data from the I-CAH registry. HORMONE RESEARCH IN PAEDIATRICS, Vol. 94(SUPPL 1) (pp 67-68)
- Re-appraising the use of urinary steroid profiles for assessing therapy control in children with 21-hydroxylase deficiency - results from the CAH-UK cohort study. HORMONE RESEARCH IN PAEDIATRICS, Vol. 94(SUPPL 1) (pp 27-27)
- Growth-Related Characteristics of Patients < 18 Years of Age with Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency (21OHD): Real-World Evidence from the I-CAH Registry. HORMONE RESEARCH IN PAEDIATRICS, Vol. 94(SUPPL 1) (pp 65-65)
- Contemporary surgical approach in CAH 46XX-Results from the I-DSD/I-CAH Registries. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 96-97)
- Development Of An International Benchmark For Sick Day Episodes As A Core Clinical Outcome In People With Congenital Adrenal Hyperplasia. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 209-210)
- Global Practice of Glucocorticoid and Mineralocorticoid Treatment in Children and Adults with Congenital Adrenal Hyperplasia - Insights from the I-CAH Registry. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 132-133)
- Investigating the roles of androgens in male reproductive development, maintenance and function by characterisation of androgen and cortisol deficient 11 beta-hydroxylase mutant zebrafish lines. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 50-50)
- Health status of children with Congenital Adrenal Hyperplasia due to 21-hydroxylase deficiency in the United Kingdom: results of a multi-centre cohort study. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 129-130)
- Development of novel non-invasive strategies for monitoring of treatment control in patients with congenital adrenal hyperplasia. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 107-107)
- The P450 side-chain cleavage isozyme cyp11a2 facilitates interrenal and gonadal steroid hormone biosynthesis in developing and adult zebrafish. HORMONE RESEARCH IN PAEDIATRICS, Vol. 91 (pp 66-67)
- Improved diagnosis and management of patients with Disorders of Sex Development (DSDs) Using Next Generation Sequencing. EUROPEAN JOURNAL OF HUMAN GENETICS, Vol. 26 (pp 202-203)
- . Hormone Research in Paediatrics, Vol. 90(Suppl 1) (pp 128-129), 27 September 2018 - 29 September 2018.
- . Endocrine Abstracts, Vol. 90(S1) (pp 146-146), 27 September 2018 - 29 September 2018.
- SDgeneMatch, A New Tool to Aid the Identification of the Genetic Causes of DSD. HORMONE RESEARCH IN PAEDIATRICS, Vol. 90 (pp 540-540)
- Revisiting the Diagnosis: Next Generation Sequencing (NGS) Identifies Concurrence of PAIS in a Previously Reported Case of Klinefelter Syndrome (47,XXY) with Hypospadias. HORMONE RESEARCH IN PAEDIATRICS, Vol. 90 (pp 562-563)
- Glucocorticoid Deficiency Causes Differentially Dysregulated Oxidative Stress Depending on the Steroidogenic Defects. HORMONE RESEARCH IN PAEDIATRICS, Vol. 90 (pp 71-72)
- The Roles of Steroids in Gonadal Development and Maintenance - Insights from a Zebrafish Model of Androgen and Cortisol Deficiency. HORMONE RESEARCH IN PAEDIATRICS, Vol. 90 (pp 53-53)
- DEFINING THE DOSE, TYPE AND TIMING OF GLUCOCORTICOID AND MINERALOCORTICOID REPLACEMENT IN 256 CHILDREN AND ADULTS WITH CONGENITAL ADRENAL HYPERPLASIA (CAH) IN THE I-CAH REGISTRY. HORMONE RESEARCH IN PAEDIATRICS, Vol. 88 (pp 358-358)
- THE PREVALENCE OF ADULTS WITH DSD CONDITIONS AT RISK OF HYPOGONADISM IN THE INTERNATIONAL DISORDERS OF SEX DEVELOPMENT REGISTRY. HORMONE RESEARCH IN PAEDIATRICS, Vol. 88 (pp 557-558)
- 17-HYDROXYLASE DEFICIENCY: RARE CAUSE OF DELAYED PUBERTY. HORMONE RESEARCH IN PAEDIATRICS, Vol. 88 (pp 255-256)
- MANAGEMENT OF FLUDROCORTISONE AND SALT THERAPY IN 0-3 YEAR OLD CHILDREN WITH CONGENITAL ADRENAL HYPERPLASIA (CAH) - PRELIMINARY ANALYSIS. HORMONE RESEARCH IN PAEDIATRICS, Vol. 88 (pp 251-252)
- Androgen Receptor Activation Stimulates Hepatic Lipid Accumulation in Human Hepatocytes. ENDOCRINE REVIEWS, Vol. 35(3)
- Phenotypic Variability and Uncommon Forms of Congenital Adrenal Hyperplasia. JOURNAL OF MEDICAL GENETICS, Vol. 48 (pp S29-S29)
- Pubertal Presentation in Congenital Adrenal Hyperplasia Due to P450 Oxidoreductase Deficiency.. ENDOCRINE REVIEWS, Vol. 31(3)
- Evidence for the Existence and Significance of an Alternative Pathway towards Androgen Synthesis in the Human Fetal Adrenal.. ENDOCRINE REVIEWS, Vol. 31(3)
- Urinary Steroid Profiling as a High-Throughput Screening Tool for the Detection of Malignancy in Patients with Adrenal Tumors.. ENDOCRINE REVIEWS, Vol. 31(3)
- . Endocrine Abstracts
- . Endocrine Abstracts
- . Endocrine Abstracts
- . Endocrine Abstracts
Preprints
- Teaching interests
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I deliver undergraduate teaching as well as postgraduate medical training and education. I teach on the MBChB course in phase 1, 2 and 3 and I am Endocrinology Phase 1 Teaching Lead.
I am module lead for the MED6100 module on the Clinical Research MSc course.
I am Deputy Director Clinical Academic Training, 91探花 Medical School and South Yorkshire and Humber Deanery. Furthermore, I am Academic training lead for paediatric clinical academic posts, University of 91探花.
- Professional activities and memberships
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Editorship
- Associate Editor: Frontiers Genomic Endocrinology since 2014
- Editorial Board: (2013-2019)
- Editorial Board: since 2015
- Editorial Board: , 2012-2015
National committees (selected)
- Chair of the Adrenal/ CAH Special Interest Groups of The (since 2021, Founding Chair)
- Member, Clinical guideline development "Diagnosis of disorders of sexual development (DSD); Member of Joint Society for Endocrinology/ BSPED DSD taskforce (2009-2011); revision of guidance in 2015, 2021
- Member of the Program Organising Committee (2016-2020)
- Chair of the Disorders of Sex Development Special Interest Groups of The (BSPED DSD SIG) (2014-2020); Founding Member of the BSPED DSD SIG 2011-2013)
International Activities (selected)
- Chair of the European Society for Paediatric Endocrinology (ESPE) program organising committee and ESPE Council Member (since 2019)
- Member of the program organising committee (POC) (2013-2019)
- UK Representative to Management Committees for (2013-2018)
- Member of the I-DSD/CAH Registry () Scientific Panel (since 2018)