Professor Alireza Fazeli
PhD
Clinical Medicine, School of Medicine and Population Health
Professor of Reproductive and Developmental Medicine
+44 114 215 9668
Full contact details
Clinical Medicine, School of Medicine and Population Health
Level 4, JW408
Jessop Wing
Tree Root Walk
91探花
S10 2SF
- Profile
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For enquiries, please contact 鈥 ClinMed-Operational@sheffield.ac.uk
I started my career as a Research Scientist at the Institute of Zoology, Zoological Society of London between 1996 and 2002. In 2002 I joined the Scholl of Medicine & Population Health where I am a Professor of Reproductive and Developmental Medicine.
Current PhD Opportunities:
- Research interests
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I am interested in the cross-talk between gametes and embryos, and the maternal tract. Since the innate immune system plays a major role in this communication I am keen to understand how the innate immunity is involved in this maternal communication.
Current projects:
- Clinical significance of Toll-like receptors expression in the diagnosis of female infertility in Saudi-Arabia, 2013-2014, Kingdom of Saudi Arabia National Guard Health Affairs, 84,706 EUR
- Broodfish epigenetic models, 2013-2014, European Union Seventh Framework Programme (FP7): Infrastructures: Aquaculture infrastructures for excellence in European fish research, (AQUAEXCEL), 40,000 EUR
- Epigenetics and periconception environment, 2012-2016, European Cooperation in Science and Technology (COST), 1,000,000 EUR
- Publications
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Show: Featured publications All publications
Featured publications
Books
Journal articles
- . Animal Reproduction Science.
- . Reproductive Biology and Endocrinology, 19(1).
- . International Journal of Molecular Sciences, 21(24).
- . Journal of Cell Communication and Signaling.
- . ACS Omega, 5(27), 16701-16710.
- . Theriogenology, 149, 104-116.
- . The Journal of Experimental Biology, 223(3).
- . Cell Communication and Signaling, 17(1).
- . Acta Dermato Venereologica, 99(13), 1258-1265.
- . Oncogene, 38(-), 1751-1763.
All publications
Books
- In quest of the perfect in vitro model.
- Proceedings of the Epiconcept Workshop 2014, 07-09 May 2014. Las Palmas, Spain: Epiconcept COST Action FA1201.
- Proceedings of the 4th General Meeting of GEMINI, 29 September - 2 October 2011. Gijon, Spain: GEMINI COST Action FA0702.
- Theriogenology: Proceedings of the GEMINI Research Workshop, Lansk, Poland, 7-9 May 2009. Elsevier.
- Proceedings of the 2nd General Meeting of GEMINI, 1-3 October 2009. Sardini, Italy: GEMINI.
- Clinical and physiological aspects of sperm zona pellucida interaction. Utrecht: Addix Wijk bij Duurstede.
Edited books
- Proceedings of the Epiconcept Conference 2014, 01-03 October 2014. Vilamoura, Portugal: Epiconcept COST Action FA1201.
- Proceedings of the Epiconcept Conference 2013, 24-25 April 2013. Antalya, Turkey: Epiconcept COST Action FA1201.
- Proceedings of the Epiconcept Workshop 2013, 13-16 October 2013. Sant Feliu de Guixols, Spain: Epiconcept COST Action FA1201.
Journal articles
- . Scientific Reports, 14(1), 25911.
- . International Journal of Molecular Sciences, 25(10), 5543-5543.
- . Journal of Extracellular Vesicles, 13(2).
- . Molecular & Cellular Proteomics, 22(11), 100642-100642.
- . International Journal of Molecular Sciences, 24(15).
- . Theriogenology, 205, 79-86.
- . International Journal of Molecular Sciences, 24(7).
- . Reproduction in Domestic Animals.
- . Environmental Biology of Fishes, 105(6), 741-751.
- . Reproductive Biology, 22(2).
- . International Journal of Molecular Sciences, 23(7).
- . Biol Reprod.
- . Reproductive Biology, 21(4), 100569-100569.
- . Biology, 10(11).
- . Membranes, 11(10).
- . Animal Reproduction Science.
- . Reproductive Biology and Endocrinology, 19(1).
- . J Mol Med (Berl).
- , 131-138.
- , 201-206.
- , 189-200.
- , 207-218.
- . International Journal of Molecular Sciences, 21(24).
- . Journal of Cell Communication and Signaling.
- . ACS Omega, 5(27), 16701-16710.
- . Theriogenology, 149, 104-116.
- . The Journal of Experimental Biology, 223(3).
- . Journal of Fish Biology, 96(2), 506-515.
- . Scientific Reports, 9(1).
- . Journal of Urology, 202(6), 1101-1101.
- . Cell Communication and Signaling, 17(1).
- . Acta Dermato Venereologica, 99(13), 1258-1265.
- . Theriogenology, 135, 121-137.
- . Oncogene, 38(-), 1751-1763.
- . Clinical and Experimental Reproductive Medicine, 45(4), 154-162.
- . International Journal of Health, Animal Science and Food Safety, 5(1s).
- . Clinical and Experimental Reproductive Medicine, 45(1), 1-9.
- . Advances in experimental medicine and biology, 1014(Periconception in Physiology and Medicine), 117-135.
- . Scientific Reports, 7.
- , 1-14.
- . Cell Journal, 17(4), 678-691.
- . Human Reproduction, 31(9), 2098-2107.
- . Theriogenology, 86(1), 438-442.
- . Theriogenology, 85(1), 105-112.
- . Annual Review of Animal Biosciences, 4(1), 291-310.
- . Biochemical Society Transactions, 43(5), 1116-1121.
- . Reproduction in Domestic Animals, 50, 27-32.
- . Human Reproduction, 30(4), 893-905.
- . MHR: Basic science of reproductive medicine, 21(6), 491-501.
- . Reproduction, Fertility and Development, 27(5), iii-iii.
- . Theriogenology, 84(5), 693-701.
- . Reproduction, Fertility and Development, 27(1), 153-153.
- . PROTEOMICS, 15(4), 649-655.
- . Reproduction Fertility and Development, 28(7), 1020-1028.
- . BMC Genomics, 15.
- . Reproduction, 147(5), 719-732.
- . Biol Reprod, 90(4), 87.
- . Reproduction in Domestic Animals, 49, 2-10.
- . BMC Genomics, 15, 487.
- . Reproduction, Fertility and Development, -.
- . PLoS One, 8(1), e39441.
- . PLoS One, 7(3), e33625.
- . IEEE/ACM Transactions on Computational Biology and Bioinformatics (ACM), 9(3), 643-654.
- . Theriogenology, 77(4), 738-765.e52.
- . Theriogenology, 77(4), 701-702.
- . Theriogenology, 77(4), 703-716.
- . Theriogenology, 77(4), 717-737.
- . Theriogenology.
- Characterisation of an in vitro system to study maternal communication with spermatozoa. Reproduction, Fertility and Development, 24, 988-998.
- . Reproduction, fertility, and development.
- . Reproduction, Fertility and Development, 24(4), 543-549.
- Antioxidant combinations are no more beneficial than individual components in combating ram sperm oxidative stress during storage at 5 掳C. Animal Reproduction Science.
- . Reproduction in Domestic Animals, 46(SUPPL. 2), 75-78.
- . Reproduction in Domestic Animals, 46(6), 1017-1021.
- . Animal Reproduction Science, 129, 180-187.
- . Reproduction, Fertility and Development, 23(8), 976-989.
- . International Journal of Developmental Biology, 55(2), 175-180.
- . Molecular Reproduction and Development, 77(11), 934-943.
- . Journal of Proteome Research, 9(7), 3412-3426.
- . Theriogenology, 73(6), 828-837.
- . Human Reproduction, 25(9), 2217-2228.
- Preface for Proceedings of the EU COST Workshop: Experimental models in animal reproduction: Theoretical and practical approaches Lansk. Theriogenology, 73(6), 711-712.
- . Journal of Reproductive Immunology, 84(1), 41-51.
- . Human Reproduction, 24(12), 3150-3159.
- . Biology of Reproduction, 81(Suppl_1), 299-299.
- . Molecular and Cellular Proteomics, 8(6), 1401-1412.
- . Reproduction, 137(2), 191-203.
- . Reproduction, Fertility and Development, 21(3), 408-418.
- . Theriogenology, 70(8), 1182-1187.
- . Reproduction in Domestic Animals, 43, 51-83.
- . Journal of Proteome Research, 7(7), 2825-2833.
- . Briefings in Functional Genomics and Proteomics, 7(2), 111-118.
- . Reproduction, Fertility and Development, 20(7), 835-845.
- . Journal of Reproductive Immunology, 77(1), 7-13.
- . Journal of Proteome Research, 6(12), 4656-4666.
- . Molecular Human Reproduction, 13(12), 845-851.
- . Journal of Proteome Research, 6(10), 3985-3994.
- . PROTEOMICS, 7(10), NA-NA.
- . Human Reproduction, 22(5), 1224-1230.
- . Journal of Proteome Research, 6(4), 1430-1439.
- . Human Reproduction, 22(2), 586-593.
- . Proteomics, 7(3), 424-435.
- . PROTEOMICS, 6(22), 5894-5897.
- . Journal of Proteome Research, 5(11), 3029-3037.
- . Molecular and Cellular Proteomics, 4(11), 1785-1796.
- . Theriogenology, 64(4), 844-854.
- . Human Fertility, 8(2), 99-158.
- . Human Reproduction, 20(5), 1372-1378.
- . Reproduction, Fertility and Development, 17(2), 282-282.
- . Reproduction, Fertility and Development, 17(7), 683-692.
- . Reproduction, Fertility and Development, 17(9), 124-124.
- . Biology of Reproduction, 71(1), 60-65.
- Evidence of sperm storage in Pipistrellus kuhlii (Chiroptera: Vespertilioniodae) in western Iran. Folia Zoologica, 53(1), 1-6.
- Abstracts of the 3rd Joint Meeting of the British Andrology Society, the British Fertility Society and the Society for Reproduction and Fertility. Aberdeen, Scotland, 13-17 July 2003.. Reprod Abstr Ser(30), 1-96.
- . Reproduction, 125(4), 509-517.
- . Biochemical Society Transactions, 31(6), 1510-1512.
- . Reproduction, 122(2), 305-315.
- Sperm interactions with epithelia and their products. Human Fertility (Camb), 3, 166-171.
- . Biology of Reproduction, 60(4), 879-886.
- . Biology of Reproduction, 59(4), 733-742.
- . International Journal of Andrology, 21(2), 57-66.
- . Reproduction in Domestic Animals, 33(1), 21-25.
- . Theriogenology, 48(4), 531-536.
- . Theriogenology, 48(5), 853-863.
- . Biology of Reproduction, 56(2), 430-438.
- Use of peanut agglutinin to assess the acrosomal status and the zona pellucida-induced acrosome eaction in stallion spermatozoa. Journal of Andrology, 17(6), 674-682.
- Inhibition of porcine sperm binding to homologous zona pellucida using hemizona assay and antibodies against zona pellucida proteins, 31(1), 233-234.
- . Reproduction in Domestic Animals, 31(1), 113-118.
- . Theriogenology, 44(1), 17-27.
- . Theriogenology, 44(5), 751-760.
- Society for the Study of Fertility and German Society for the Study of Fertility and Sterility, Winter meeting. Aachen, December 1993. Abstracts.. J Reprod Fertil Abstr Ser(12), 1-72.
- Use of sperm binding to homologous hemizona pellucida to predict stallion fertility. Equine Veterinary Journal, 25, 57-59.
- Repeated transvaginal ultrasound-guided follicle aspiration in the mare. Equine Veterinary Journal, 75-78.
- . The Veterinary record, 132(1), 14-16.
- Society for the Study of Fertility. British Fertility Society. Joint meeting. Bristol, 16-18 December 1992. Abstracts.. J Reprod Fertil Abstr Ser(10), 1-64.
- Assessment of sperm cell membrane integrity in the horse.. Acta veterinaria Scandinavica. Supplementum, 88, 49-58.
- . Frontiers in Plant Science, 15, 1477614.
- . Frontiers in Cell and Developmental Biology, 12.
- . Frontiers in Molecular Biosciences, 11.
- . Communications Biology, 7(1).
- . Biomolecules, 14(6), 626-626.
- . Frontiers in Cell and Developmental Biology, 12, 1382552.
- . International Journal of Molecular Sciences, 25(9), 4759-4759.
- . Biomolecules, 13(2), 279-279.
- . Veterinary Research Communications.
- . International Journal of Molecular Sciences, 23(24), 16051-16051.
- . Journal of Cell Communication and Signaling.
- . International Journal of Molecular Sciences, 21(15), 5365-5365.
- . Bioscientifica Proceedings.
- . Reproduction Abstracts.
- . Reproduction Abstracts.
- . Statistics in Medicine, 29(7-8), 711-711.
- . Molecular Ecology.
- . Andrologia, 23(4), 296-296.
Chapters
- , Principles of Gender-Specific Medicine (pp. 7-24). Elsevier
- In Quest of the Perfect In Vitro Model Preface, NEXT GENERATION CULTURE PLATFORMS FOR RELIABLE IN VITRO MODELS (pp. V-VI).
- , Encyclopedia of Reproduction (pp. 269-275). Elsevier
- , Reference Module in Biomedical Sciences Elsevier
- , Principles of Gender-Specific Medicine (pp. 251-267). Elsevier
- , Principles of Gender-Specific Medicine (pp. xvii-xviii). Elsevier
- Periconception in Physiology and Medicine Preface, PERICONCEPTION IN PHYSIOLOGY AND MEDICINE (pp. V-VI).
Conference proceedings papers
- Whole-genome microRNA expression profiles from single pre-ovulatory follicles of oocyte donors and polycystic ovarian syndrome (PCOS) patients. HUMAN REPRODUCTION, Vol. 35 (pp 1448-1449)
- . British Journal of Dermatology, Vol. 177(5) (pp E294-E295). London, UK, 30 November 2017 - 2 December 2017.
- . Animal Reproduction, Vol. 14(3) (pp 630-634)
- Localization of toll like receptors (TLRs) in human fallopian tube epithelial cells. HUMAN REPRODUCTION, Vol. 31 (pp 317-317)
- Enhancement of Animal Production by Foetal Imprintings/Epigenetics. REPRODUCTION IN DOMESTIC ANIMALS, Vol. 50 (pp 27-28)
- The role of microRNAs in mediating a state of enhanced endometrial receptivity in response to trophoblast cells: an integrative analysis. HUMAN REPRODUCTION, Vol. 30 (pp 106-106)
- Designing molecular beacons for microRNA detection in the periconceptional environment. Epigenetics and Periconception Environment, 01-03 October 2014. Vilamoura, Portugal
- Can periconception diet affect seahorse male reproductive success?. Aquaculture Europe 14. San Sebastian, Spain, 14-17 October 2014
- Our changing view of the periconceptional environment: its importance and regulation. 26th Congress of the Polish Physiological Society, Vol. 65 (pp 64-64). Szczecin, Poland
- Understanding the potential mechanisms involved in TLR3 induced implantation failure using an in vitro human implantation model. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 16-16). 91探花, United Kingdom
- The developing pig embryo modulates the microRNA expression profile of the endometrium. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 17-17). 91探花, United Kingdom
- Characterisation of Tribbles-2 modulation of TLR5 signalling pathway. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 15-15). 91探花, United Kingdom
- The dynamic uterine environment: meeting the immune and metabolic demands of the early pig embryo. Epiconcept Conference 2013, 24-25 April 2013 (pp 69-69). Antalya, Turkey
- Seahorses: A new and unique epigenetic model. Epiconcept Workshop 2013, 13-16 October 2013 (pp 59-59). Sant Feliu de Guixols, Spain
- The developing pig embryo modulates the microRNA expression profile of the endometrium. Epiconcept Workshop 2013, 13-16 October 2013 (pp 46-46). Sant Feliu de Guixols, Spain
- Estradiol modulates Toll-like receptor 5-mediated AP-1 transcriptional activity. Epiconcept Conference 2013, 24-25 April 2013 (pp 61-61). Antalya, Turkey
- The pig uterus distinguishes between vitrified and fresh embryos. 17th Conference of the European Society for Domestic Animal Reproduction, ESDAR, 12-14 September 201. Bologna, Italy
- Activation of uterine innate immune system affects embryo implantation and endometrial receptivity. 3rd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie (pp 7-7). 91探花, United Kingdom
- Understanding the potential mechanisms involved in implantation failure induced by TLR3 activation in vitro. Epiconcept Conference 2013, 24-25 April 2013 (pp 121-121). Antalya, Turkey
- Estradiol decreases NF-kappa B activation through GPR30 and ER alpha. Epiconcept Conference 2013, 24-25 April 2013 (pp 120-120). Antalya, Turkey
- Estradiol decrease NF-母B activation through GPR30 and ER alpha. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. 91探花, United Kingdom
- Understanding the potential mechanisms involved in implantation failure induced by TLR3 activation in vitro. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. 91探花, United Kingdom
- Nano-scale membrane alterations are induced by the activation of TLR 2 and 2/6 in endometrial epithelial cells. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. 91探花, United Kingdom
- Understanding the TLR9 intracellular signalling pathway involved in mediating the reduction of trophoblast cells binding to epithelial cells in vitro. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. 91探花, United Kingdom
- Effect of Heat Shock Protein HSPA8 on bull sperm cryopreservation. 2nd Symposium of the Academic Unit of Reproductive and Developmental Medicine, University of Sheffie. 91探花, United Kingdom
- Exogenous HSPA8 increases sperm viability via a cholesterol-dependent membrane interactions mechanism. Annual Meeting of the British Andrology Society: Testicular dysfunction and the infertile patient, 1. University of Bradford, Bradford, United Kingdom
- Toll-like receptor 3 activation reduces trophoblast cells binding to endometrial cells in human. Medical School Annual Research Meeting 2012, 11-12 June 2012 (pp 49-49). University of 91探花, 91探花, United Kingdom
- Embryo-maternal communication. 28th Scientific Meeting of the European Embryo Transfer Association, 07-08 September 2012. Saint Malo, France
- Toll-like receptor 9 activation reduces trophoblast cells binding to endometrial cells in vitro. Medical School Annual Research Meeting 2012, 11-12 June 2012 (pp 54-54). University of 91探花, 91探花, United Kingdom
- Modelling sperm behaviour in a 3D environment. Proceedings of the 9th International Conference on Computational Methods in Systems Biology, CMSB'11 (pp 141-149). Paris, France, 21 September 2011 - 23 September 2011.
- 3D Modelling of Complex Biological Structures: The Oviduct.. TPCG (pp 255-262)
- Using computational systems biology to investigate sperm navigation and transport in the female reproductive tract. Systems Biology in Maternal Communication with Gametes and Embryo. Opatija, Croatia, 9 May 2010 - 13 May 2010.
- Activation of Toll-like receptor 5 decreases attachment of human trophoblast cells to endometrial cells. University of 91探花 Medical School Research Meeting 5-6 July 2010. 91探花, United Kingdom
- . Proceedings of the 9th Int. Workshop on Parallel and Distributed Methods in Verification, PDMC 2010 - Joint with the 2nd Int. Workshop on High Performance Computational Systems Biology, HiBi 2010 (pp 78-87)
- The Virtual Oviduct: An Essential Tool for the Application of Computational Biology Approaches to Investigation of Maternal Interaction with Gametes and Embryo. BIOLOGY OF REPRODUCTION (pp 115-115)
- Embryoid bodies from human embryonic stem cells form a niche for male germ cell development in vitro. PAPERS CONTRIBUTED TO THE 9TH INTERNATIONAL CONGRESS OF ANDROLOGY. (pp 169-174). Barcelona, Spain, 7 March 2009 - 10 March 2009.
- Innate immunity is influence by sex hormones in fallopian tube. REPRODUCTION IN DOMESTIC ANIMALS, Vol. 43 (pp 66-66)
- Sex hormones enhance TLR3 response to its specific ligand in human Fallopian tube epithelial cells. BIOLOGY OF REPRODUCTION (pp 197-197)
- . JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Vol. 71(2) (pp 152-152)
- Harnessing the biology of the oviduct for the benefit of artificial insemination.. Society of Reproduction and Fertility supplement, Vol. 62 (pp 247-259)
- Profiling porcine oviductal epithelial cell surface membrane proteins.. BIOLOGY OF REPRODUCTION (pp 202-202). Lodi, Italy, 20 February 2006 - 21 February 2006.
- Boar spermatozoa alter the oviductal secretory proteome.. BIOLOGY OF REPRODUCTION (pp 221-222)
- Peripheral bound membrane proteins are involved in the maintenance of boar sperm viability by oviductal apical plasma membrane preparations in vitro. MOL BIOL CELL, Vol. 12 (pp 117A-117A)
- Isthmic apical plasma membrane preparations maintain boar sperm viability in vitro in a dose dependent manner.. BIOL REPROD, Vol. 62 (pp 259-259)
- . Human Fertility, Vol. 3(3) (pp 166-171)
- The influence of steroidal sex hormones on the expression of TLR5 in different human endometrial cell lines. Infection, Inflammation and Immunity Research Day, University of 91探花. 91探花, United Kingdom, 11 January 2008.
- Porcine sperm-head receptor interaction with proteins peripherally bound to the oviductal lumen. Reproduction Fertility and Development. Copenhagen, Denmark, 8 January 2005 - 12 January 2005.
- Analysis of oviduct flow based on histological data. 17th Congress of the European Society of Biomechanics. University of Edinburgh, Edinburgh, United Kingdom, 5 July 2010 - 8 July 2010.
- Profiling porcine oviductal epithelial cell surface membrane proteins. 38th Annual Meeting of the Society for the Study of Reproduction. Quebec City, Canada, 24 July 2005 - 27 July 2005.
- Intracellular proteomic analysis of embryonic carcinoma cells. Infection, Inflammation and Immunity Research Day, University of 91探花. 91探花, United Kingdom, 11 January 2008.
- Identification and characterization of the oviductal epithelial cell surface proteome. Expanding Proteomics: New Directions in Biology, Chemistry, Pharmaceutical Sciences and Medicine, An. Zurich, Switzerland, 5 December 2005 - 7 December 2005.
- Global profiling of the oviductal epithelial cells plasma membrane surface proteins. Human Fertility. Warwick, United Kingdom, 2 April 2005 - 6 April 2005.
- The activation of the endometrial TLR-2 affect human trophoblast cells binding to endometrial cells in vitro. Periconceptional Developmental Programming, GEMINI COST Action FA0702. Jerusalem, Israel, 31 May 2011 - 3 June 2011.
- The effect of apical plasma membrane fractions of porcine oviduct on boar sperm capacitation. Journal of Reproduction and Fertility Abstract Series. Warwick, United Kingdom, December 1999.
- Postnatal growth in four Pipistrllus kuhli reared in a flight cage. 13th International Bat Research Conference. Miko艂ajki, Poland, 23 August 2004 - 27 August 2004.
- The proteomic profile of cells reprogrammed using human embryonic carcinoma cell extracts. 6th Annual Meeting of the International Society for Stem Cell Research. Philadelphia, United States, 11 June 2008 - 14 June 2008.
- The proteomic profile of cells reprogrammed using human embryonic carcinoma cell extracts. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 9 June 2008 - 10 June 2008.
- Characterisation of the proteomic profile of cells reprogrammed using embryonic carcinoma cell extracts. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006.
- Nuclear reprogramming: exploring the proteome. 3rd United Kingdom Stem Cell Meeting: Epigenetics and Differentiation. Regents College, London, United Kingdom, 11 March 2008.
- The characterisation of cell surface markers in cells reprogrammed using cellular extracts. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 19 June 2007.
- The effect of storage methods on the sperm zona binding in the horse. Society for the Study of Reproduction. Caxambu, Brazil, 7 August 1994 - 13 August 1994.
- Somatic cell nuclear reprogramming using Xenopus laevis oocyte extract. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 12 June 2006 - 13 June 2006.
- Porcine oviductal epithelial cells obtained from prepubertal gilt oviducts can induce boar sperm capacitation in vitro. Journal of Reproduction and Fertility Abstract Series. University of Birmingham, Birmingham, United Kingdom, 13 November 1998 - 14 November 1998.
- Transvaginal ultrasound guided ovum pick-up in the horse, recovery rate and oocyte quality. Journal of Reproduction and Fertility Abstract Series. Aachen, Germany, December 1993.
- Localization and variable expression of Gai2 in human endometrium and Fallopian tubes. 2nd International Student Award and Congress in Reproductive Medicine. Yazd, Iran, 11 May 2007 - 13 May 2007.
- Toll-like receptor 3 activation reduces trophoblast cells binding to endometrial cells in human. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Effect of HSPA8 on boar sperm viability. 31st Annual Meeting of the British Andrology Society. Belfast, United Kingdom, 19 January 2009 - 20 January 2009.
- Localization and variable expression of G伪i2 in human reproductive tissues. Human Embryonic Stem Cells - Progress Towards Cell Medicine, International Symposium, University of . 91探花, United Kingdom, 14 July 2006.
- Hormonal regulation of G伪i2 and mPRa in a human Fallopian tube epithelial cell line. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 19 June 2007.
- Effect of extracellular HSPA8 on boar sperm membrane fluidity. Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Soustons, France, 1 October 2010 - 2 October 2010.
- The effect of extracellular HSPA8 on boar sperm membrane fluidity and its relation to capacitation. 32nd Annual Meeting of the British Andrology Society. Alderley Park, United Kingdom, 9 November 2010 - 10 November 2010.
- Embryo alters uterine proteomic profile. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Toll-like receptor 9 activation inhibits trophoblast cells binding to endometrial cells in vitro. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Influence of extracellular HSPA8 (HSC70) on boar sperm viability and membrane fluidity. Heat Shock Proteins in Cancer and Immunology. Woods Hole, MA, United States, 7 November 2010 - 11 November 2010.
- Acrosomal status of boar semen bound to homologous hemi-zona determined by fluorescent staining. Journal of Reproduction and Fertility Abstract Series. Aachen, Germany, December 1993.
- Toll-like receptors and pregnancy: embryo(s) as modulators of innate immune response. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Spermatozoa alter oviductal secretory proteome. Human Fertility. Warwick, United Kingdom, 2 April 2005 - 6 April 2005.
- Brief exposure of spermatozoa to HSPA8 enhances fertilisation and monospermy in a porcine in vitro fertilisation system. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Lactose specifically inhibits sperm binding to porcine isthmic oviductal epithelial cells in vitro. Journal of Reproduction and Fertility Abstract Series. Edinburgh, United Kingdom, 31 July 2000 - 2 August 2000.
- Cell surface protein trafficking in oviductal cells in response to spermatozoa. 7th Siena Meeting from Genome to Proteome: Back to the Future. Siena, Italy, 3 September 2006 - 7 September 2006.
- A global quantitative profiling technology to investigate cell surface protein trafficking. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006.
- Gametes alter the oviductal secretory proteome in vivo. 36th Annual Conference of the Society for Reproductive Biology. Perth, Australia, 4 September 2005 - 7 September 2005.
- Assessment of a porcine sperm-oviduct culture system using frozen-thawed oviductal cells. Journal of Reproduction and Fertility Abstract Series. York, United Kingdom, July 1997.
- Transcriptome and proteome dynamics of Synecocystis sp. PCC 6803 during light-dark cycling. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006.
- Sperm-zona binding; an additional parameter to assess quality of bull semen. Journal of Reproduction and Fertility Abstract Series. Paris, France, 13 December 1991 - 14 December 1991.
- The development of a hemi-zona assay for porcine sperm. 12th International Congress on Animal Reproduction. The Hague, The Netherlands, 23 August 1992 - 27 August 1992.
- Preferential binding of uncapacitated boar spermatozoa to porcine oviductal epithelial cells in vitro. 8th International Symposium on Spermatology. Montreal, Canada, 17 August 1998 - 22 August 1998.
- Female reproductive tract has a sperm recognition system. Human Fertility. Warwick, United Kingdom, 2 April 2005 - 6 April 2005.
- Sperm-zona binding in the bovine is not influenced by the day to day variations in ejaculates. Journal of Reproduction and Fertility Abstract Series. Aachen, Germany, 16 December 1992 - 16 December 1992.
- Transcriptome alteration in mouse oviduct 6 hours after mating. Gordon Research Conferences: Reproductive Tract Biology. New London, Connecticut, United States, 30 June 2002 - 5 July 2002.
- Fertility-related proteins in oviduct: HSPA8, a brief history. 23rd annual Meeting of the AI-Vets. Prague, Czech Rebuplic, 19 October 2011 - 21 October 2011.
- Maternal communication with gametes and embryo; from in vivo to in silico. 7th International Conference on Boar Semen Preservation. Bonn, Germany, 14 August 2011 - 17 August 2011.
- Alcohol and ketone metabolisms of Sulfolobus solfataricus. Integrative Proteomics: Structure, Function, and Interaction. 3rd Joint Meeting of the British Socie. Cambridge, United Kingdom, 12 July 2006 - 14 July 2006.
- Non-glycosylated peripheral proteins of the sow oviduct are involved in the maintenance of boar sperm viability in vitro. Journal of Reproduction and Fertility Abstract Series. Aberdeen, United Kingdom, 13 July 2003 - 17 July 2003.
- The sperm zona pellucida binding assays: capacitation, the acrosome reaction and sperm function assessment methods. British Andrology Society Workshop, 1993.
- Induction of true acrosome reaction in stallion spermatozoa by preovulatory follicle fluid aspirated from oestrus mares. 2nd International Symposium on Stallion Semen. Amersfoort, The Netherlands, 7 March 1996 - 8 March 1996.
- Computational modelling of sperm movements within the oviduct. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Using computational modelling to understand sperm transport and navigation in the female reproductive tract. 32nd Annual Meeting British Andrology Society. AstraZeneca Pharmaceuticals, Alderley Park, United Kingdom, 9 November 2010 - 10 November 2010.
- Hydrogen breath test in foals. 6th International Symposium on Equine Reproduction. Caxambu, Brazil, 7 August 1994 - 13 August 1994.
- Procedural reconstruction of a three dimensional graphical model of an oviduct. 1st General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Volos, Greece, 9 October 2008 - 11 October 2008.
- Isolation and characterization of tryptic peptides of fetuin and porcine zona pellucida and investigation of their possible physiological function in sperm-egg interaction. Annual Conference of Physiology and Pathology of Reproduction. Leipzig, Germany, 1995.
- Influence of thawing method on motility, plasma membrane integrity and morphology of frozen-thawed stallion spermatozoa. 2nd International Symposium on Stallion Semen. Amersfoort, The Netherlands, 7 March 1996 - 8 March 1996.
- A maternal-embryo dialogue exits at very early stages of pregnancy. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Sex-hormones influence TLR5 responses to flagellin. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Embryos elicit a local response in the maternal tract. Medical School Research Meeting, University of 91探花. 91探花, United Kingdom, 5 July 2010 - 6 July 2010.
- A systems biology approach for understanding maternal communication with embryo. Research Training School GEMINI COST Action FA0702, Systems Biology in Maternal Interactions with Ga. Opatija, Croatia, 9 May 2010 - 13 May 2010.
- Proceedings of the 2nd General Meeting of GEMINI, 1-3 October 2009. Sardini, Italy
- Proceedings of the GEMINI Research Training School, 9-13 May 2010. Opatija, Croatia
- Proceedings of the 3rd General Meeting of GEMINI, 1-3 October 2010. Soustons, France
- Understanding innate immunity in maternal-embryo interaction. 4th General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Gijon, Spain, 29 September 2011 - 2 October 2011.
- Pig embryo at blastocyst stage elicits a local response in sow endometrium. 2nd General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Alghero, Italy, 1 October 2009 - 3 October 2009.
- Characterisation of an in vitro system to study the female reproductive tract interaction with spermatozoa. University of 91探花 Medical School Research Meeting. 91探花, United Kingdom, 5 July 2010 - 6 July 2010.
- Determination of different factors influencing the outcomes of an in vitro model of sperm-oviductal cell interaction. 3rd General Meeting of Maternal Interaction with Gametes and Embryos, GEMINI Cost Action FA0702. Soustons, France, 1 October 2010 - 2 October 2010.
- A systemic approach to characterise and define an in vitro model to study the female reproductive tract interaction with spermatozoa. A case study.. Research Training School GEMINI COST Action FA0702, Systems Biology in Maternal Interactions with Ga. Opatija, Croatia, 9 May 2010 - 13 May 2010.
- Establishment of a defined in vitro model for investigation of maternal interactions with gametes and embryo. 31st Annual British Andrology Society Meeting. Belfast, United Kingdom, 19 November 2009 - 20 November 2009.
- Establishment of a defined in vitro model for investigation of maternal interactions with gametes and embryo. 5th International Gulf Conference of Saudi Society of Obstetric and Gynaecology. Jeddah, Saudi Arabia, 21 March 2010 - 25 March 2010.
- The expression of TLRs during the menstrual cycle and the potential effect of sex hormones on their expression. 1st International Student Congress on Medical Research. Shiraz, Iran, 23 May 2007 - 25 May 2007.
- The expression of TLRs during the menstrual cycle and the potential effect of sex hormones on their expression and function. 2nd International Student Award and Congress in Reproductive Medicine. Yazd, Iran, 11 May 2007 - 13 May 2007.
- The expression of TLRs during the menstrual cycle. Human Embryonic Stem Cells - Progress Towards Cell Medicine, International Symposium, University of . 91探花, United Kingdom, 14 July 2006.
- The expression of TLRs during the menstrual cycle and the potential effect of sex hormones on their expression. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 12 June 2006 - 13 June 2006.
- Regulation of innate immunity in Fallopian tubes by Toll-like receptors and their role in female infertility. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 19 June 2007.
- Expression of TLRs in Fallopian tube and the effect of sex hormone on their expression. Infection, Inflammation and Immunity Research Day, University of 91探花. 91探花, United Kingdom, 11 January 2008.
- Infertility, Innate immunity in the female infertility with emphesize on TLRs. 10th Congress on Reproductive Biomedicine. Tehran, Iran, 23 September 2009 - 25 September 2009.
- Expression of TLRs in Fallopian tube and the effect of sex hormone on their expression. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 19 June 2007.
- Expression of TLRs in Fallopian tube, the combination and separate effect of sex hormones on their expression. Iranian Journal of Reproductive Medicine. Shiraz, Iran, 3 March 2010 - 5 March 2010.
- Synergistic effects of sex hormone on the expression and function of TLRs in an immortalized Fallopian tube cell line. Toll2008 - Recent Advances in pattern Recognition. Lisbon, Portugal, 24 September 2008 - 27 September 2008.
- Infertility, innate immunity and female reproductive tract. 3rd International Student Award and Congress in Reproductive Medicine. Yazd, Iran, 17 April 2009 - 19 April 2009.
- Differentiation of human ES cells to primordial germ cells in vitro. Fertility 2005, 4th Joint meeting of the British Fertility Society, British Andrology Society and th. Warwick, United Kingdom, 2 April 2005 - 6 April 2005.
- Synergistic effects of sex hormone on the expression and function of TLRs in an immortalized fallopian tube cell line. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 9 June 2008 - 10 June 2008.
- The expression of Toll-like receptor TLR2, TLR3 and TLR4 by human endometrial adenocarcinoma cell lines Ishikawa and Hec-1B. Medical School Research Day, University of 91探花. 91探花, United Kingdom, 19 June 2007.
- Potential of human embryonic stem cells to differentiate to primordial germ cells in vitro. International Congress and Student Award in Reproductive Medicine. Yazd, Iran, 28 December 2005 - 29 December 2005.
Reports
- Research group
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Postgraduate Students
- Shagayegh Basatvat
- Nurul Jamaludin
- Nasim Maslehat
- Mehrnaz Montazeri
- Tamer Nafee
- Javier Sanchez-Lopez
Research Support Staff
- Sarah Elliott
- Laszlo Tecsi
- Teaching interests
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- Train postgraduate research students through MSc and PhD programs in different aspects of maternal communication with gametes and embryo and innate immunity.
- Contribute to the education of postgraduate students on the MSc in Reproductive and Developmental Medicine course.
- Coordinate the Reproduction module of Phase 1B in the MBChB Medicine undergraduate course and contribute to the Student Selected Components.
- Mentor undergraduate and postgraduate students.
- Professional activities and memberships
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- Trustee of the Infertility Research Trust.
- Vice-chairman and grant holder of the `Epigenetics and Periconception Environment麓 collaborational research project funded by the European Cooperation in Science and Technology (COST Action FA1201) (2012-2016).
- Member of the Postgraduate Research Committee for the Department of Human Metabolism.
- Graduate selector for the Academic Unit of Reproductive and Developmental Medicine.
- Panel member in the Research Grant Review Committee of Royal Society, the Biotechnology and Biological Sciences Research Council (BBSRC) and Irish Research and Technology Council.
- Member of the Editorial Board for the journal `Reproduction麓.
- Invited presenter on 50 international meetings.
- Organiser of 17 scientific conferences.
- Regular external examiner in PhD student thesis and promotion panels.