Professor Albert CM Ong
MA, DM, FRCP, FAoP, FERA
Clinical Medicine, School of Medicine and Population Health
Professor of Renal Medicine
+44 114 215 9542
Full contact details
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
91探花
S10 2RX
- Profile
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For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
Albert Ong is Professor of Renal Medicine at the University of 91探花, UK. He studied medicine at the University of Oxford and trained as a physician-scientist at University College London and Oxford. He held senior research fellowships from Kidney Research UK and the Wellcome Trust at Oxford and 91探花. His scientific research focuses on the molecular basis of cyst formation, the biological basis for disease variability and drug discovery in autosomal dominant polycystic kidney disease (ADPKD). He founded and leads specialist services for ADPKD and other genetic kidney diseases at the 91探花 Kidney Institute. His work has been recognised through several national and international awards, including the ISN Lillian Jean Kaplan International Prize. As a key opinion leader, he continues to provide strategic advice and leadership internationally. He currently serves as Co-Director of the MRC-NIHR UK Renal Ciliopathies National Network (CILIAREN) and as a member of the ERA Council.
- Research interests
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My long-term research goals are to understand the molecular basis of cyst formation and the determinants of biological variation with the aim of developing novel therapies in ADPKD. Current areas of investigation are the role of cytoskeletal dysregulation in cyst initiation, changes in RNA metabolism in disease progression and the genetic basis of neonatal-onset PKD.
Projects:
- Role of compartmentalised GTPase signalling in polycystin regulation of actin structure and dynamics
- Non-coding RNAs as biomarkers of disease activity and as therapeutic targets
- RNA-binding proteins as key mediators of disease initiation and progression in ADPKD
- Complex genetics underlying very-early onset PKD
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . Nature Reviews Nephrology, 1-13.
- . Nephrology Dialysis Transplantation.
- . Kidney International Reports.
- . Kidney International Reports, 8(5), 989-1001.
- . American Journal of Kidney Diseases.
- . Kidney International, 100(3), 513-515.
- . Genetics in Medicine.
- . JCI Insight, 5(16).
- . Kidney International, 98(2), 420-435.
- . Cellular Signalling, 71.
- . Nature Reviews Nephrology, 14(3), 146-148.
- . The Lancet, 389(10081), 1780-1782.
- . Journal of the American Society of Nephrology, 27(4), 1159-1173.
- . Kidney International, 88(4), 699-710.
- . The Lancet, 385(9981), 1993-2002.
- . Lancet, 361(9359), 774-776.
- . J Biol Chem, 277(23), 20763-20773.
- . Kidney Int, 56(4), 1324-1333.
- . Am J Pathol, 154(6), 1721-1729.
- . Proc Natl Acad Sci U S A, 93(4), 1524-1528.
All publications
Journal articles
- . Nephrology Dialysis Transplantation, 39(Supplement_1).
- . Nephrology Dialysis Transplantation, 39(Supplement_1).
- . Nature Reviews Nephrology, 1-13.
- . The Lancet, S0140-6736(23)02843.
- . The Journal of Gene Medicine, 26(2), e3674.
- . Nephrology Dialysis Transplantation.
- . PLOS ONE, 19(1).
- . Kidney International Reports.
- . Kidney International Reports.
- . Kidney International Reports.
- . Seminars in Nephrology, 43(2), 151405-151405.
- . Human Mutation, 2023.
- . Advances in Kidney Disease and Health, 30(3), 294-302.
- . Clinical Kidney Journal.
- . Nephrology Dialysis Transplantation.
- . Kidney International Reports, 8(3), S244-S245.
- . Kidney International Reports, 8(5), 989-1001.
- . Nephrology Dialysis Transplantation, 38(3), 527-531.
- . Clinical Kidney Journal, 16(3), 403-407.
- . American Journal of Kidney Diseases.
- . European Journal of Preventive Cardiology.
- . Journal of Medical Genetics.
- . Kidney Medicine.
- . Journal of Hepatology, 77, S814-S814.
- . Clinical Kidney Journal, 15(8), 1439-1446.
- . BMJ Open, 12(6).
- . Clinical Kidney Journal.
- . Kidneys, 11(1), 37-39.
- . Nephrology Dialysis Transplantation, 37(Supplement_3).
- . Nephrology Dialysis Transplantation, 37(Supplement_3).
- . Clinical Kidney Journal, 15(6), 1034-1036.
- . Nephrology Dialysis Transplantation.
- . Clinical Kidney Journal.
- . Human Molecular Genetics.
- . The American Journal of Human Genetics.
- . Kidney International, 100(3), 513-515.
- . Human Molecular Genetics.
- . Clinical Kidney Journal.
- . Renal Failure, 43(1), 1-15.
- . International Journal of Molecular Sciences, 21(23).
- . Genetics in Medicine.
- . BMJ Open, 10(10).
- . Journal of the American Society of Nephrology, 31(10S), 502-502.
- . Journal of the American Society of Nephrology, 31(10S), 502-502.
- . JCI Insight, 5(16).
- . American Journal of Kidney Diseases.
- . Cellular Signalling, 72.
- . Kidney International.
- . Kidney International, 98(2), 420-435.
- . Kidney International, 98(2), 404-419.
- . Nature, 584(7819), E2-E2.
- . Cellular Signalling, 71.
- . Nephrology Dialysis Transplantation, 35(Supplement_3).
- . Nature.
- . American Journal of Kidney Diseases.
- . Kidney International.
- . American Journal of Kidney Diseases.
- . BMJ Open, 10(1).
- . Scientific Reports, 10(1).
- . Kidney International, 97(2), 370-382.
- . Frontiers in Neurology, 10.
- . Kidney International Reports, 4(7), S48-S48.
- . Kidney International Reports, 4(7), S148-S148.
- . Proceedings of the National Academy of Sciences, 116(27), 13320-13329.
- . Nephrology,Dialysis and Transplantation.
- . European Radiology, 1-10.
- . Nephrology.
- . Radiology.
- . Kidney International, 94(6), 1053-1068.
- . Nephrology Dialysis Transplantation, 33(Sup 2), ii4-ii14.
- . Nephrology Dialysis Transplantation, 33(4), 563-573.
- . Am J Kidney Dis.
- . BMC Nephrology, 19(1).
- . Nature Reviews Nephrology, 14(3), 146-148.
- . Nephrology Dialysis Transplantation, 32(12), 2144-2144.
- . Trials, 18(1).
- . Journal of the American Society of Nephrology, 28(10), 2973-2984.
- . Nephrology Dialysis Transplantation.
- . The Lancet, 389(10081), 1780-1782.
- . Nephrology Dialysis Transplantation, 32(suppl_3), iii94-iii94.
- . American Journal of Physiology - Renal Physiology, 312(4), F577-F588.
- . Kidney International, 91(3), 575-586.
- . The Lancet, 389, S90-S90.
- . F1000Research, 5, 2029-2029.
- . Nephrology Dialysis Transplantation, 31(suppl_1), i22-i23.
- . Nephrology Dialysis Transplantation, 31(3), 337-348.
- . Journal of the American Society of Nephrology, 27(4), 1159-1173.
- . Nephrology Dialysis Transplantation, 31(7), 1130-1140.
- . BMJ Open, 5(11).
- . Kidney International, 88(4), 699-710.
- . Journal of Biological Chemistry, 290(39), 23888-23896.
- . Kidney International, 88(1), 17-27.
- . The Lancet, 385(9987), 2576-2576.
- . Nephrology Dialysis Transplantation, 30(suppl_3), iii190-iii190.
- . The Lancet, 385(9981), 1993-2002.
- . Biomolecular NMR Assignments, 9(2), 369-373.
- . Nephrology Dialysis Transplantation, 30(suppl_3), iii63-iii63.
- . Nephrology Dialysis Transplantation, 30(2), 197-203.
- . Seminars in Nephrology, 35(2), 197-207.
- . Transplantation, 99(5), 1023-1029.
- . Value in Health, 17(7), A564-A564.
- . Nephrology Dialysis Transplantation, 29(suppl_4), iv26-iv32.
- . Nephrology Dialysis Transplantation, 29(suppl 4), iv121-iv123.
- . Nephrology Dialysis Transplantation, 29(suppl 4), iv106-iv112.
- . The Lancet, 383(9931), 1844-1859.
- . Nephrol Dial Transplant, 29 Suppl 3, iii73-iii78.
- . Pharmacol Res, 80, 43-51.
- . Nephrology Dialysis Transplantation, 29(12), 2353-2353.
- . Nephrology Dialysis Transplantation, 29(suppl 4), iv15-iv25.
- . Kidney International, 86(6), 1244-1252.
- . Small, 10(1), 60-65.
- . British Journal of Clinical Pharmacology, 76(4), 524-535.
- . Nephron Clin Pract, 124(1-2), 31-37.
- . ACS Nano, 7(9), 8214-8223.
- . PLoS ONE, 8(8).
- . Nephrol Dial Transplant, 28(11), 2661-2663.
- . QJM, 106(7), 639-646.
- . Hum Mol Genet, 22(10), 1924-1939.
- . Pflugers Archiv European Journal of Physiology, 1-14.
- . Am J Physiol Heart Circ Physiol, 304(1), H33-H41.
- . Pediatr Nephrol, 28(1), 33-49.
- . Nephrology Dialysis Transplantation, 27(1), 67-69.
- . NEPHRON CLINICAL PRACTICE, 120(1), C25-C34.
- . QJM, 105(7), 693-696.
- mTOR signaling is differentially affected in human renal cells with PKD1 or PKD2 mutations. PEDIATR NEPHROL, 26(9), 1648-1648.
- . Contrib Nephrol, 172, 200-209.
- . J Biol Chem, 286(21), 18994-19000.
- . Am J Physiol Renal Physiol, 300(6), F1375-F1384.
- . NEPHRON CLIN PRACT, 118(1), C3-C8.
- . Medicine, 39(2), 119-125.
- . Mol Biol Cell, 21(22), 3853-3865.
- . EMBO J, 29(7), 1176-1191.
- . Biophysical Journal, 98(3), 344a-344a.
- Structural and Molecular Basis of the Assembly of the TRPP2/PKD1 Complex. BIOPHYSICAL JOURNAL, 98(3), 343A-343A.
- . BMJ, 339(oct13 2), b4204-b4204.
- . Am J Pathol, 175(4), 1493-1503.
- . BMJ, 339, b3763.
- . Exp Physiol, 94(8), 914-927.
- . Clin Med (Lond), 9(3), 278-283.
- . J Cell Sci, 122(Pt 9), 1410-1417.
- . Nephron Clin Pract, 112(4), c230-c241.
- . Journal of Cell Science, 122(10), 1702.
- . Proceedings of the National Academy of Sciences of the United States of America, 106(28), 11558-11563.
- . J Biol Chem, 283(42), 28471-28479.
- . EMBO J, 27(9), 1345-1356.
- . Nephron Physiol, 108(1), p1-p7.
- . Kidney Int, 72(2), 157-165.
- . J Am Soc Nephrol, 18(2), 560-569.
- . Transplantation, 83(1), 36-40.
- . American Journal of Pathology, 170(3), 830-842.
- . Human Molecular Genetics, 16(3), 265-275.
- . Nephrol Dial Transplant, 21(8), 2078-2084.
- . Hum Mol Genet, 15(9), 1465-1473.
- . Am J Kidney Dis, 45(6), 1096-1099.
- . Kidney Int, 67(4), 1234-1247.
- . J BIOL CHEM, 279(26), 27472-27481.
- . J Am Soc Nephrol, 14(7), 1804-1815.
- . Medicine, 31(5), 32-35.
- . Lancet, 361(9359), 774-776.
- . Lancet, 361(9376), 2196-2201.
- . Nephron Exp Nephrol, 93(2), e80.
- . Nephrol Dial Transplant, 17(12), 2138-2144.
- Genotype/phenotype correlations in ADPKD: Vascular complications.. J AM SOC NEPHROL, 13, 40A-40A.
- Polycystin-1 mediates cell-cell adhesion in PKD1 transgenic and non-transgenic lines. J AM SOC NEPHROL, 13, 46A-46A.
- . J Biol Chem, 277(23), 20763-20773.
- Polycystin expression in the kidney and other tissues: Complexity, consensus and controversy. EXP NEPHROL, 8(4-5), 208-214.
- . Exp Nephrol, 8(4-5), 208-214.
- Endothelin antagonists in renal disease. KIDNEY INT, 57(4), 1778-1794.
- . Kidney Int, 56(4), 1324-1333.
- Polycystin expression in PKD-1, infantile PKD-1 and TSC-2/PKD-1 cystic tissue: heterogenous expression of the normal allele in cystic epithelia.. KIDNEY INT, 55(6), 2559-2559.
- . Am J Pathol, 154(6), 1721-1729.
- . Kidney Int, 55(5), 2091-2116.
- Characterisation and expression of the PKD-1 protein, polycystin, in renal and extrarenal tissues.. KIDNEY INT, 55(5), 2091-2091.
- An unusual complication of pregnancy. NEPHROL DIAL TRANSPL, 14(5), 1324-1326.
- . Nephrol Dial Transplant, 14(5), 1324-1326.
- Cyst formation in ADPKD: new insights from natural and targeted mutants. NEPHROL DIAL TRANSPL, 14(3), 544-546.
- . Nephrol Dial Transplant, 14(3), 544-546.
- . Endothelium, 6(1), 61-70.
- Characterisation, cellular expression, tissue localisation and developmental modulation of the PKD-1 product, polycystin.. J AM SOC NEPHROL, 8, A1744-A1744.
- Polycystin expression in PKD-1, infantile PKD-1 and TSC-2/PKD-1 cystic kidney: Evidence against a two-hit disease mechanism in cyst initiation.. J AM SOC NEPHROL, 8, A1745-A1745.
- . Am J Hum Genet, 60(6), 1399-1410.
- . Lancet, 349(9058), 1039-1040.
- Renal disease. II. The polycystic kidney disease 1 (PKD-1) gene: an important clue in the study of renal cyst formation.. J R Coll Physicians Lond, 31(2), 141-146.
- The polycystic kidney disease 1 (PKD-1) gene: An important clue in the study of renal cyst formation. Journal of the Royal College of Physicians of London, 31(2), 141-146.
- Mutation defection in polycystic kidney disease 1 (PKD1) gene.. J AM SOC NEPHROL, 7(9), A1856-A1856.
- . Hum Mol Genet, 5(4), 539-542.
- . Proc Natl Acad Sci U S A, 93(4), 1524-1528.
- . Bone, 18(2), 159-169.
- . Nephrol Dial Transplant, 11(2), 251-257.
- Surprising new roles for endothelins - Mutant mice reveal the first clear links to human disease. BRIT MED J, 312(7025), 195-196.
- . BMJ, 312(7025), 195-196.
- Screening the 3' region of the polycystic kidney disease 1 (PKD1) gene reveals six novel mutations. AM J HUM GENET, 58(1), 86-96.
- Surprising new roles for endothelins - Mutant mice reveal the first clear links to human disease. British Medical Journal, 312(7025), 195-196.
- Screening the 3' region of the polycystic kidney disease 1 (PKD1) gene reveals six novel mutations.. Am J Hum Genet, 58(1), 86-96.
- CHARACTERIZATION OF THE POLYCYSTIC-KIDNEY-DISEASE-1 (PKD1) PROTEIN, POLYCYSTIN. J AM SOC NEPHROL, 6(3), 713-713.
- ENDOTHELIN DEPENDENT AND INDEPENDENT GROWTH SYSTEMS INVOLVED IN HUMAN PROXIMAL TUBULAR AUTOREGENERATION. J AM SOC NEPHROL, 6(3), 773-773.
- . Kidney Int, 48(2), 390-401.
- . Bone, 16(6), 679-679.
- A HYPOXIA-INDUCIBLE, ENDOTHELIN-1 MEDIATED, AUTOCRINE GROWTH LOOP INVOLVED IN HUMAN RENAL TUBULAR REGENERATION. KIDNEY INT, 47(2), 693-693.
- Cell-cell cross-talk in the pathogenesis of renal interstitial fibrosis. Kidney International, Supplement(49).
- . Kidney Int, 46(5), 1315-1321.
- AUTOREGENERATION OF HUMAN PROXIMAL TUBULAR CELLS MEDIATED BY A HYPOXIA-INDUCIBLE ENDOTHELIN-1 (ET-1) GROWTH LOOP. J AM SOC NEPHROL, 5(3), 699-699.
- HUMAN TUBULAR-DERIVED ENDOTHELIN IN THE PARACRINE REGULATION OF RENAL INTERSTITIAL FIBROBLAST FUNCTION. EXP NEPHROL, 2(2), 134-134.
- . Kidney Int, 45(3), 753-762.
- Human tubular-derived endothelin in the paracrine regulation of renal interstitial fibroblast function.. Exp Nephrol, 2(2), 134.
- . Kidney Int, 45(2), 345-351.
- . Am J Kidney Dis, 23(2), 205-209.
- . Nephrol Dial Transplant, 9(5), 471-472.
- . Eur J Clin Invest, 23(5), 259-265.
- . Nephrol Dial Transplant, 8(8), 748-753.
- ISOLATION OF THE NA+/H+ ANTIPORTER GENE EXPRESSED IN HUMAN PROXIMAL TUBULE CELLS. DIABETOLOGIA, 35, A56-A56.
- TUBERCULOUS PERITONITIS COMPLICATING PERITONEAL-DIALYSIS - A CASE FOR EARLY DIAGNOSTIC LAPAROTOMY. NEPHROL DIAL TRANSPL, 7(5), 443-446.
- Tuberculous peritonitis complicating peritoneal dialysis: a case for early diagnostic laparotomy?. Nephrol Dial Transplant, 7(5), 443-446.
- . Int J Cardiol, 30(3), 364-366.
- . Clin Endocrinol (Oxf), 34(1), 43-49.
- EFFECTS OF NORADRENALINE INFUSION ON CARDIAC-OUTPUT AND SYSTOLIC-TIME INTERVALS DERIVED FROM ELECTRICAL BIOIMPEDANCE CARDIOGRAPHY. BRIT J CLIN PHARMACO, 29(5), P639-P640.
- . Eur Heart J, 11(4), 368-371.
- Effects of noradrenaline infusion on cardiac output and systolic time intervals derived from electrical bioimpedance cardiography. British Journal of Clinical Pharmacology, 29(5).
- . Nephrol Dial Transplant, 5(10), 904-905.
- . J Hypertens Suppl, 7(6), S166-S167.
- . Postgrad Med J, 65(767), 660-661.
- . Int J Cardiol, 21(1), 71-73.
- . Kidney360.
- . Trials, 25(1).
- . Frontiers in Immunology, 14.
- . Frontiers in Cell and Developmental Biology, 11, 1192935.
- . Orphanet Journal of Rare Diseases, 18(1).
- . Clinical Kidney Journal.
- . Nephrology Dialysis Transplantation.
- . Nephrology Dialysis Transplantation.
- .
Chapters
- , Oxford Textbook of Clinical Nephrology (pp. 2625-2626). Oxford University Press
- , Oxford Textbook of Clinical Nephrology (pp. 2627-2633). Oxford University Press
- , Genomic Medicine (pp. 369-392). Oxford University Press
- , Pathologies of Calcium Channels (pp. 491-522). Springer Berlin Heidelberg
- , Genomics and Clinical Medicine (pp. 195-212). Oxford University PressNew York, NY
- , Medicine and Surgery (pp. xi-xii). Elsevier
Conference proceedings papers
- A Polycystin-1-Bicaudal C1 complex regulates focal adhesion function through integrin beta-1, F-actin organisation and local translation in HKE cells. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 39 (pp I219-I219)
- Clinical spectrum and prognosis of the atypical polycystic kidney disease caused by monoallelic loss-of-function IFT140 variants. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 39 (pp I213-I214)
- . Abstracts
- Patients with polcystic liver disease have longer waiting times but better clinical outcomes following liver transplantation in the UK. JOURNAL OF HEPATOLOGY, Vol. 77 (pp S814-S814)
- THE INTERACTION OF GENDER AND GENOTYPE IN THE DEVELOPMENT OF POLYCYSTIC LIVER DISEASE IN ADPKD. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 37 (pp I7-I7)
- FAMILIAL CLUSTERING OF A RARE UMOD VARIANT IN UNDIAGNOSED HEREDITARY NEPHROPATHY SUGGESTS THE PRESENCE OF A COMMON ANCESTRAL FOUNDER MUTATION. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 37 (pp I14-I15)
- FLANK PAIN HAS A MAJOR NEGATIVE IMPACT ON HEALTH-RELATED QUALITY OF LIFE IN ADPKD: THE CYSTIC I STUDY. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 36
- REDUCED QUALITY OF LIFE IN ADPKD PATIENTS WITH CKD STAGE 1-3: THE CYSTIC I QUALITY OF LIFE STUDY. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 35 (pp 98-98)
- . Kidney International Reports, Vol. 5(3) (pp S185-S185). Abu Dhabi, United Arab Emirates, 26 March 2020 - 29 March 2020.
- CLINICAL PRESENTATION AND PROGNOSIS OF DNAJB11-ASSOCIATED NEPHROPATHY: AN INTERNATIONAL COLLABORATIVE STUDY. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 34
- GLOBAL MICRORNA PROFILING IN HUMAN URINARY EXOSOMES REVEALS NEW DISEASE BIOMARKERS AND CELLULAR PATHWAYS FOR AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD). NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 34
- . Ultraschall in der Medizin, 14 November 2018 - 16 November 2018.
- PATIENT AND CAREGIVER BELIEFS, ATTITUDES AND PERSPECTIVES ON GENETIC SCREENING AND TESTING FOR AUTOSOMAL POLYCYSTIC KIDNEY DISEASE. NEPHROLOGY, Vol. 23 (pp 88-88)
- VERY EARLY-ONSET AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE DUE TO BI-ALLELIC MUTATIONS IN PKD1 AND PKD2. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 32 (pp 94-94)
- . Nephrology Dialysis Transplantation, Vol. 31(suppl_1) (pp i22-i22)
- SELECTIVE PROSTAGLANDIN E2 RECEPTOR BLOCKADE FOR THE TREATMENT OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 31 (pp 22-23)
- . Biophysical Journal, Vol. 110(3) (pp 611a-612a)
- . Nephrology Dialysis Transplantation, Vol. 30(suppl_3) (pp iii85-iii86)
- INCREASED PSYCHOSOCIAL BURDEN AND ADVERSE QUALITY OF LIFE IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 30
- . NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 30
- DEVELOPMENT OF A MODEL TO PREDICT DISEASE PROGRESSION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD). NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 29 (pp 75-75)
- . HEART, Vol. 97(20) (pp 12-12)
- Molecular genetic basis of inherited thrombocytopenia. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 342-342)
- Regulation of polycystin-1 mediated intercellular adhesion by phosphorylation in renal epithelia cells. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 575A-575A)
- A Ca2+-activated conductance in cultured mouse collecting duct cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 80A-80A)
- Upregulation of polycystin-2 expression following experimental ischaemic renal injury.. J AM SOC NEPHROL, Vol. 13 (pp 113A-113A)
Preprints
- Research group
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- Dr Andrew Streets
- Dr Manoj Valluru
- Dr Rebecca Walker
- Dr Joshua Griffiths
- Dr Matthew Gittus
- Dr Zhu Zhou
- Mr Patryk Zarecki
- Teaching activities
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I have had a long-standing commitment to postgraduate nephrology training especially to develop clinical and non-clinical academics in renal science and in enhancing nephrology training for young nephrologists for the developing 鈥榯wo-thirds鈥 world.
I served as Deputy Director for Clinical Academic Training at 91探花 (2020-2023), having previously served as Academic Programme Director for Nephrology. I was a member of the ISN Fellowship Committee (2019-2023), the Scientific Advisory Board of the ERA (2016-2022) and was a member of the UK Renal Association Executive committee as Chair of the International Committee (2009-2013).
- Professional activities and memberships
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National and International Committees
- European Renal Association 鈥 Council member
- European Renal Association - Scientific Program Chair 61st ERA Congress 2024
- MRC-NIHR Renal Ciliopathies National Network 鈥 Co-Director
- CYSTic Consortium 鈥 Chief investigator
- ADPKD in Europe Consortium - Co-chair
- European ADPKD Forum 鈥 Faculty member
Editorial Boards
- Faculty of 1000 Medicine, Nephrology faculty
- Theme Editor, Nephrology Dialysis Transplantation
Advisory Boards
- Mayo Translational PKD Centre, Mayo Clinic, Rochester - External Faculty
- Renal Genomic England Clinical Interpretation Partnership (GeCIP) 鈥 Co-chair for Cystic Diseases (2017-2023)
- National Institute for Clinical Excellence (NICE) Technology Appraisal of Tolvaptan for ADPKD - Nominated Clinical Expert (2013-2015)
National and International Guidelines
- UK Kidney Association Working Group for Tolvaptan in ADPKD 鈥 Chair
- Kidney Diseases Improving Global Outcomes (KDIGO) ADPKD Guideline Initiative 鈥 Working group and Theme lead
- Standardised Outcomes in Nephrology鈥揚KD (SONG-PKD) 鈥 Steering committee