Professor Cindy Cooper
BSc (Pharmacology and Physiology), PhD (Neuropharmacology)
Population Health, School of Medicine and Population Health
Director, Clinical Trials Research Unit
Professor of Health Services Research and Clinical Trials
+44 114 222 0743
Full contact details
Population Health, School of Medicine and Population Health
3037
Regent Court (ScHARR)
30 Regent Street
91探花
S1 4DA
- Profile
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Professor Cindy Cooper is Director of 91探花 Clinical Trials Research Unit (CTRU) and Professor of Health Services Research and Clinical Trials.
After graduating in Pharmacology and Physiology from the University of Manchester and completing a PhD in neuropharmacology at the University of Nottingham, she worked at 91探花 and West Yorkshire Health Authorities. She joined ScHARR in 1996 to establish the North Trent Research Office, to provide support to local NHS organisations to develop research strategy and increase their research income. She has been involved in health services research and clinical trials for over twenty five years and has held the position of Professor of Health Services Research and Clinical Trials since January 2014.
Cindy has previously held positions on NIHR funding bodies including being a member of the Programme Grant for Applied Research Committee and the COVID Call College of Experts as well as Chair of the Yorkshire and Humber Research for Patient Benefit Committee. Cindy is Chair of three NIHR funded Project Steering Committees and a member of the UKCRC Clinical Trials Unit (CTU) Executive Group. She has extensive experience of designing and implementing evaluations of complex health interventions in large multi-centre trials and other study designs. Since 2013 she has been PI or co-applicant on 15 NIHR Health Technology Assessment, Public Health Research, Clinical Trials Unit (CTU) Efficient Trials call and Programme Grant for Applied Research grants related to trials and trials methodology to a total research cost of 拢12 million. She has also held CTU support and infrastructure awards to total cost of approximately 拢1.1 million. Cindy has published over 100 peer-reviewed research papers. The CTRU currently has a portfolio of around 20 studies, the majority being clinical trials or studies of trial methodology.
Cindy is module coordinator for the ScHARR MSc module on clinical trials research methodology and has supervised six PhD students to successful completion, one of these was an NIHR Clinical Fellowship and one a Stroke Association Fellowship.
- Research interests
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- Trials methodology, particularly pilot (external and internal) and feasibility studies
- Psycho-social aspects of long term conditions
- Health technology evaluation
- Evaluation of psychotherapeutic interventions
- Public and patient involvement in research
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- . Trials, 19.
- . Clinical Trials, 15(2), 189-196.
- . BMJ, 356.
- . The Lancet, 389(10068), 538-546.
- . Health Technology Assessment, 20(89), 1-64.
- . Statistical Methods in Medical Research, 25(3), 1057-1073.
- . The Lancet Neurology, 14(9), 883-892.
- . Journal of Clinical Epidemiology, 68(3), 347-354.
- . Trials, 12, 259.
All publications
Journal articles
- . The Cognitive Behaviour Therapist, 17.
- . The Lancet, 403(10444), 2619-2629.
- . The Lancet.
- . European Journal of Neurology.
- . Neurology, 102(17_supplement_1).
- . BMJ Open, 14(3).
- . Trials, 25(1), 163.
- . Pilot and Feasibility Studies, 10(1).
- . Journal of Clinical Epidemiology, 111275-111275.
- . BMJ Open, 14(2).
- . Journal of the Neurological Sciences, 455, 121832-121832.
- . British Journal of Dermatology, 189(3), e42-e43.
- . Mental Health and Physical Activity, 100547-100547.
- . Autism.
- . International Journal of Environmental Research and Public Health, 20(3).
- . Research Methods in Medicine & Health Sciences.
- . Frontiers in Child and Adolescent Psychiatry, 1.
- . The Lancet, 400(10353), 680-690.
- . Journal of Child Psychology and Psychiatry.
- . Research Methods in Medicine & Health Sciences.
- . Research Methods in Medicine & Health Sciences.
- . Health Technology Assessment, 26(24), 1-151.
- . BMC Medical Research Methodology, 22(1).
- . The Lancet Healthy Longevity, 3(4), e276-e285.
- . Clinical Nutrition ESPEN.
- . BMJ Open, 12(1).
- . Chronic Illness.
- . Pharmaceutical Statistics.
- . Brain and Behavior.
- . Qual Life Res.
- . Stroke.
- . Journal of Clinical Epidemiology.
- . BMC Geriatrics, 21(1).
- . Clinical Interventions in Aging, 16, 231-244.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 22(5-6), 350-359.
- . BMC Emerg Med, 21(1), 13.
- . British Paramedic Journal, 5(3), 15-22.
- . Clinical Rehabilitation.
- . Frontiers in Neurology, 11.
- . Clinical Nutrition, 39(8), 2547-2556.
- . BMJ Open, 10(7).
- . Journal of Attention Disorders.
- . Health Technology Assessment, 24(19), 1-176.
- . Trials, 21.
- . British Journal of Health Psychology, 24(4), 953-969.
- . BMJ Open, 9(10).
- . The Lancet Neurology, 18(9), 821-833.
- . Health Technology Assessment, 23(47), 1-176.
- . Health Technology Assessment, 23(49), 1-144.
- . BMJ Open, 9(9).
- . BMJ Open, 9(5).
- . Trials, 19(1), 578-578.
- . Trials, 19.
- . BMJ Open, 8(8).
- . Pilot and Feasibility Studies, 4(1).
- . BMJ Open, 8(4).
- . BMJ Open, 8(4).
- . Clinical Trials, 15(2), 189-196.
- . Qualitative Health Research, 28(8), 1295-1307.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 19(5-6), 351-361.
- . Obstetric Anesthesia Digest, 37(4), 202-203.
- . Emergency Medicine Journal.
- . Obstetrical & Gynecological Survey, 72(6), 323-325.
- . Clinical Radiology.
- . Health Technology Assessment, 21(20), 1-278.
- . BMJ, 356.
- . The British Journal of Psychiatry, 210(5), 362-367.
- . Trials, 18.
- . BMJ Open, 7(e013537).
- . The Lancet, 389(10068), 538-546.
- . Health Technology Assessment, 20(93), 1-154.
- . Health Technology Assessment, 20(89), 1-64.
- . European Child & Adolescent Psychiatry, 25(11), 1217-1231.
- . Pilot and Feasibility Studies, 2(1).
- . BMC Psychiatry, 16.
- . BMC Public Health, 16(649).
- . Health Technol Assess, 20(45), 1-186.
- . Int J Epidemiol, 45(3), 707-712.
- . Statistical Methods in Medical Research, 25(3), 1057-1073.
- . Amyotrophic Lateral Sclerosis && Frontotemporal Degeneration, 17(5-6), 313-324.
- . Diabetic Medicine, 33(2), 243-251.
- . Trials, 16(1).
- . Health Technology Assessment, 19(101), 1-174.
- . Trials, 16(1).
- . The Lancet Neurology, 14(9), 883-892.
- . Journal of Clinical Epidemiology, 68(3), 347-354.
- . Trials, 16(S2).
- . International Journal of Obesity, 39(3), 535-541.
- . European Journal of Health Economics, 16(2), 141-151.
- . Public Health Research, 2(7).
- . Thorax, 69(12), 1105-1112.
- . BMC Psychiatry, 14, 5.
- . Diabetes Research and Clinical Practice, 106(3), 443-450.
- . Emergency Medicine Journal, 31(e1), e40-e45.
- . BMJ Open, 4(9), e006204-e006204.
- . Contemp Clin Trials, 38(2), 338-343.
- . Health and Quality of Life Outcomes, 12(1).
- . Trials, 15, 141.
- . Qual Health Res, 24(1), 46-54.
- . Health Technol Assess, 18(13), 1-210.
- . Trials, 14(S1).
- . Trials, 14(S1).
- . Trials, 14(1).
- . Health (London), 16(6), 602-618.
- . Stroke, 43(7), 1904-1911.
- Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial. Respiratory Medicine, 106(6), 802-810.
- . Disabil Rehabil, 34(18), 1540-1549.
- . BMC Neurol, 12, 74.
- . Heart, 98(2), 170-171.
- . Heart, 98(4), 312-318.
- . Emerg Med J, 29(3), 233-238.
- . Trials, 12, 259.
- . AGE AGEING, 40(5), 557-562.
- . Acad Emerg Med, 18(5), 488-495.
- . BMC Public Health, 11, 129.
- . BMC Public Health, 11, 640.
- . Health Expectations.
- . International Journal of Consumer Studies, 35(6), 609-615.
- . Heart, 97(3), 190-196.
- . J SOCIOL, 46(1), 63-82.
- Principles of Design of Access with Evidence Development Approaches A Consensus Statement from the Banff Summit. PHARMACOECONOMICS, 28(2), 109-111.
- . BMC Med Res Methodol, 10, 67.
- . BMJ, 340, c1786.
- . BMC Public Health, 10, 3.
- . Psychol Health, 25(6), 699-712.
- . Ethn Health, 14(4), 359-377.
- . Health Expect, 12(2), 209-220.
- . Health Technol Assess, 13(39), 1-iv.
- . BMC Neurol, 9, 1.
- . Health Soc Care Community, 16(6), 606-613.
- . Health Expect, 10(4), 380-391.
- Multiple sclerosis and retention of employment: Experience within the risk sharing scheme. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 78(9), 1033-1033.
- . J Epidemiol Community Health, 61(3), 205-210.
- . J Epidemiol Community Health, 61(3), 198-204.
- . BMC Fam Pract, 8, 62.
- . Health Policy, 75(3), 280-297.
- The health status of gypsy travellers in England. EUR J PUBLIC HEALTH, 14(4), 13-13.
- . Health Expect, 7(3), 209-220.
- . Public Health, 117(1), 31-35.
- . Journal of Human Nutrition and Dietetics, 15(1), 33-37.
- . Health Policy, 61(2), 213-236.
- Quality of referrals to gynaecologists: Towards consensus. Journal of Clinical Governance, 10(4), 177-181.
- . British Journal of Clinical Governance, 7(2), 92-103.
- MEASUREMENT OF CATECHOLAMINES, INDOLEAMINES, THYROTROPIN-RELEASING-HORMONE AND SUBSTANCE-P IN RAT AND HUMAN SPINAL-CORD USING A COMMON EXTRACTION METHOD. JOURNAL OF NEUROSCIENCE METHODS, 1(22), 31-39.
- . BMC Medical Research Methodology, 24(1).
- . BMJ, e077418-e077418.
- . NIHR Open Research, 4, 12-12.
- . Trials, 25(1).
- . Research Methods in Medicine & Health Sciences.
- . Health Technology Assessment, 1-114.
- . JMIR Rehabilitation and Assistive Technologies, 10, e47542-e47542.
- . Public Health Research, 1-137.
- . BMC Neurology, 22(1).
- . Health Technology Assessment, 26(39), 1-100.
- . Health Technology Assessment, 26(42), 1-174.
- . Journal of Human Nutrition and Dietetics.
- . Health Technology Assessment, 25(7), 1-92.
- . BMJ, i195-i195.
- . BMJ, h5627-h5627.
- . PLOS ONE, 10(11), e0141104-e0141104.
- . Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
- . Health Technology Assessment, 19(66), 1-130.
- . BMJ Open.
Chapters
- , Handbook of Statistical Methods for Randomized Controlled Trials (pp. 243-274). Chapman and Hall/CRC
- Evaluating the impact of public involvement on research, Critical Perspectives on User Involvement (pp. 217-223).
- Should we? Could we? Measuring involvement, Critical Perspectives on User Involvement (pp. 209-216).
Conference proceedings papers
- . British Paramedic Journal, Vol. 4(3) (pp 53-54). Cardiff, Wales, 24 September 2019 - 24 September 2019.
- Staff training to improve participant recruitment into surgical randomised controlled trials: a feasibility study embedded within four randomised controlled trials. TRIALS, Vol. 20
- PROMoting THE USE of SWATs (PROMETHEUS): Routinely embedding recruitment and retention interventions within randomised trials. TRIALS, Vol. 20
- Identifying barriers and enablers of adherence to self-directed aphasia computer therapy: a patient and carer perspective. INTERNATIONAL JOURNAL OF STROKE, Vol. 12 (pp 23-23)
- Behavioural activation therapy for depression after stroke (BEADS): a feasibility randomised controlled pilot trial of a psychological intervention for post-stroke depression. INTERNATIONAL JOURNAL OF STROKE, Vol. 12 (pp 15-15)
- . Trials, Vol. 18(Suppl 1) (pp 91-91). Liverpool, UK, 7 May 2017 - 10 May 2017.
- Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. TRIALS, Vol. 18
- Quantifying effect sizes in clinical trials. TRIALS, Vol. 18
- Defining and measuring the components of a complex neuro-rehabilitation intervention for aphasia. INTERNATIONAL JOURNAL OF STROKE, Vol. 11 (pp S19-S19)
- . 1.6 General Practice and Primary Care
- . Trials, Vol. 16(S2)
- Differential reporting of group sequential RCTs: shortcomings ofthe CONSORT 2010 statement. CPS 11: Group Sequential Methods and Interim Analysis. ARLINGTON, VIRGINIA, USA, 17 May 2015 - 20 May 2015.
- . Trials, Vol. 14(Suppl 1) (pp O124-O124)
- The acceptability of cognitive behavioural therapy software for the treatment of depression in people with multiple sclerosis. J EPIDEMIOL COMMUN H, Vol. 62 (pp A12-A13)
- How appropriate is cognitive behavioural therapy computer software for the treatment of depression in people with multiple sclerosis?. MULTIPLE SCLEROSIS JOURNAL, Vol. 14 (pp S263-S264)
- The multiple sclerosis monitoring study: Progress to date. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 75(8) (pp 1214-1214)
Posters
Other
Preprints
- Teaching interests
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I am co-ordinator for the Randomised Controlled Trials in Health and Social Care module of the MSc in Clinical Research.
I am interested in supervising research students in areas such as RCT methodology, evaluation of health technologies, particularly psychotherapeutic interventions and psychosocial aspects of chronic conditions.
- Professional activities and memberships
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- Director of the Clinical Trials Research Unit
- Chair of University Health Research Governance Committee 2011 - 2019
- Member of the NIHR CTU Directors Executive Group 2015 -
- Trial Management Group member for Journeying through Dementia, CACTUS, ACUTE, ASPECT, I-Socialise and OPTION DM trials
- Member of the York Trials Unit Strategic Advisory Group
- Member of the UKCRC CTU Directors Meeting
- Member of the NIHR Clinical Trials Unit Standing Advisory Committee 2016 -
- Member of the 91探花 Teaching Hospital Foundation Trust Research Innovation and Education Committee 2016-2019
- Member of the Programme Grant for Applied Research Assessment Panel D 2017 -
- Chair of the Trial Steering Committee for the York University lead, HTA Funded:-ACTIVE (articular type C pilon fracture Trial Internal vs External Fixation) Trial. 2017 -
- Chair of the Trial Steering Committee for the York University lead, NIHR Programme Grant Funde: MODS (Multi-morbidity in OLder Adults with Depression Study) 2019 -
Current Projects
- CACTUS (Clinical and cost effectiveness of aphasia computer therapy compared with usual stimulation or attention control long term post stroke. HTA 2013-2018. 拢1.7 million.
- OPTION DM Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM) trial. HTA Project: 15/35/03. 拢2.9 million 01/06/2016 to: 31/08/2019 .
- The ACUTE (Ambulance CPAP: Use, Treatment effect and Economics) feasibility study: A pilot randomised controlled trial of prehospital CPAP for acute respiratory failure. HTA: 15/08/40, 2016-1019. 拢378,285
- ASPECT A non inferiority randomised controlled trial comparing the clinical and cost effectiveness of single session treatment with multi-session CBT in children with specific phobias. HTA 15/38/04 . 2016-2020.拢1.4 million
- NIHR CTU Support Funding 拢350,000 per annum
- Journeying through Dementia is a large-scale research study that aims to find out whether attending a 12-week community programme has a positive impact on the quality of life for people who are living with the early stages of dementia.
- The COMMEND project (NIHR HTA 16/81/010) includes two phases. Phase 1 will adapt ACT for people with MND and test the acceptability and feasibility of the adapted ACT intervention and whether it is possible to conduct a larger study.
- High CALS. A programme to develop and evaluate a complex intervention to achieve a high calorie diet in ALS (HighCALS) 42 months 02/04/2018 - 01/03/2024. NIHR PGfAR 拢1,871,107.00 (IA 6% - 拢112,266.42. CI - C McDermott
- MSS 3. NIHR HS&DR Funded RCT - MSS3: Multiple Symptoms Study 3: pragmatic trial of a community based clinic for patients with persistent (medically unexplained) physical symptoms. Co-I.UoS allocation - 拢898,732.57.
- MATTS. Major Trauma Triage Tool Study. NIHR HTA funded. CI- Dr Gordon Fuller
- I-SOCIALISE Investigating SOcial Competence and Isolation in children with Autism taking part in LEGO-based therapy clubs In School Environments (I-SOCIALISE), NIHR PHR Funded